Method of inhibiting quorum sensing in Pseudomonas aeruginosa

A method of inhibiting quorum sensing in Pseudomonas aeruginosa is provided. The method comprises contacting Pseudomonas aeruginosa with a gold(I) thiolate complex in an amount effective to inhibit quorum sensing in the Pseudomonas aeruginosa. Use of the method for the treatment or prevention of dam...

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Hauptverfasser: Hong, Ziyan, Givskov, Michael Christian, Tan, Zhen Wei Leon, Yang, Liang, Chng, Shu Sin
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creator Hong, Ziyan
Givskov, Michael Christian
Tan, Zhen Wei Leon
Yang, Liang
Chng, Shu Sin
description A method of inhibiting quorum sensing in Pseudomonas aeruginosa is provided. The method comprises contacting Pseudomonas aeruginosa with a gold(I) thiolate complex in an amount effective to inhibit quorum sensing in the Pseudomonas aeruginosa. Use of the method for the treatment or prevention of damage or disease associated with quorum sensing and/or biofilm formation in a subject, or for the treatment of biofilm and/or for inhibiting biofilm formation is also provided.
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subjects AGRICULTURE
ANIMAL HUSBANDRY
BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PEST REPELLANTS OR ATTRACTANTS
PLANT GROWTH REGULATORS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF
TRAPPING
title Method of inhibiting quorum sensing in Pseudomonas aeruginosa
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