Amino-substituted heterocyclic derivatives as sodium channel inhibitors

The present invention relates to novel aminoindazolyl derivative compounds of Formula(I), the use of said compounds in treating diseases mediated by modulation of voltage-gated sodium channels in particular Nav1.7 AND to compositions containing said derivatives.

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Hauptverfasser: Rae, Alastair, Duffy, James, Chambers, Mark Stuart, Sharpe, Andrew, Goldsmith, Michael Daniel, Lemasson, Isabelle Anne, Fonquerna Pou, Silvia, Osborne, James
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creator Rae, Alastair
Duffy, James
Chambers, Mark Stuart
Sharpe, Andrew
Goldsmith, Michael Daniel
Lemasson, Isabelle Anne
Fonquerna Pou, Silvia
Osborne, James
description The present invention relates to novel aminoindazolyl derivative compounds of Formula(I), the use of said compounds in treating diseases mediated by modulation of voltage-gated sodium channels in particular Nav1.7 AND to compositions containing said derivatives.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Amino-substituted heterocyclic derivatives as sodium channel inhibitors
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