Cells producing Fc-containing molecules having altered glycosylation patterns and methods and use thereof

The present application relates to the field of glyco-engineering, more specifically to glyco-engineering of Fc-containing molecules, such as antibodies. It is shown herein that Fc-containing molecules with a specific glycosylation pattern have a considerably longer circulating half-life in vivo, wi...

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Bibliographische Detailangaben
Hauptverfasser: Santens, Francis, Callewaert, Nico L. M
Format: Patent
Sprache:eng
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