6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one compounds and their use as negative allosteric modulators of mGluR2 receptors

The present invention relates to novel 6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one derivatives as negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 2 ("mGluR2"). The invention is also directed to pharmaceutical compositions comprising such compounds, to p...

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Hauptverfasser: Alonso-de Diego, Sergio Alvar, Delgado-González, Óscar, Van Gool, Michiel Luc Maria, Andrés-Gil, José Ignacio, De Lucas Olivares, Ana Isabel, Trabanco-Suárez, Andrés Avelino
Format: Patent
Sprache:eng
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