CDK-INHIBITING DERIVATIVES OF 4-(IMIDASOL-5-YL)-2-(4-SULFOANILINO)PYRIMIDINE

Compounds of the formula (I): wherein R', R2, R3, R4, R5 and p are as defined within and a pharmaceutically acceptable salts and in vivo hydrolysable esters are described. Also described are processes for their preparation and their use as medicaments, particularly medicaments for producing a c...

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Hauptverfasser: THOMAS ANDREW PETER, NEWCOMBE NICHOLAS JOHN
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creator THOMAS ANDREW PETER
NEWCOMBE NICHOLAS JOHN
description Compounds of the formula (I): wherein R', R2, R3, R4, R5 and p are as defined within and a pharmaceutically acceptable salts and in vivo hydrolysable esters are described. Also described are processes for their preparation and their use as medicaments, particularly medicaments for producing a cell cycle inhibitory (anti-cell-proliferation) effect in a warm-blooded animal, such as man. (I)
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title CDK-INHIBITING DERIVATIVES OF 4-(IMIDASOL-5-YL)-2-(4-SULFOANILINO)PYRIMIDINE
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