Crystalline forms of ret inhibitor and preparation thereof

Provided herein are methods of preparing crystalline, selpercatinib Form A, which contains little to none of the thermodynamically more stable, crystalline selpercatinib Form B. Selpercatinib is useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, incl...

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Hauptverfasser:	MERRITT, JEREMY MILES, BHARDWAJ, RAJNI MIGLANI, SELBO, JON GORDON
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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