Mixed metal compound, the pharmaceutical compositions containing the same, and the uses therefor

There is provided a method of producing a mixed metal compound comprisingat least Mg2+and at least Fe3+having an aluminium content of less than 10000 ppm,having an average crystal size of less than 20nm (200A)comprising the steps of:(a) combining a Mg2+salt and a Fe3+salt with Na2CO3and NaOH to prod...

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Hauptverfasser: APPLEWHITE, RICHARD JONATHAN, NEWTON, MAURICE SYDNEY, RICKARD, CHRISTOPHER JOHN, MORRISON, JAMES DAVID, RHODES, NIGEL PETER
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creator APPLEWHITE, RICHARD JONATHAN
NEWTON, MAURICE SYDNEY
RICKARD, CHRISTOPHER JOHN
MORRISON, JAMES DAVID
RHODES, NIGEL PETER
description There is provided a method of producing a mixed metal compound comprisingat least Mg2+and at least Fe3+having an aluminium content of less than 10000 ppm,having an average crystal size of less than 20nm (200A)comprising the steps of:(a) combining a Mg2+salt and a Fe3+salt with Na2CO3and NaOH to produce a slurry, wherein the pH of the slurry is maintained at from 9.5 to 11 , and wherein the Na2CO3is provided at an excess of 0 to 4.0 moles than is required to complete the reaction(b) subjecting the slurry to mixing under conditions providing a power per unit volume of 0.03 to 1.6kW/m3(c) separating the mixed metal compound from the slurry, to obtain a crude product having a dry solid content of at least 10 wt%(d) drying the crude product either by(i) heating the crude product to a temperature of no greater than 150°C and sufficient to provide a water evaporation rate of 0.05 to 1.5 kg water per hour per kg of dry product, or(ii) exposing the crude product to rapid drying at a water evaporation rate of 500 to 50
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subjects CHEMISTRY
COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSESC01D OR C01F
HUMAN NECESSITIES
HYGIENE
INORGANIC CHEMISTRY
MEDICAL OR VETERINARY SCIENCE
METALLURGY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Mixed metal compound, the pharmaceutical compositions containing the same, and the uses therefor
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