Compound and pharmaceutical composition for tumor imaging and tumor therapy
A compound represented by formula (I) is provided, wherein in formula (I), R1 and R2 each independently represents hydrogen, O-R3 or S-R4, at least one of R1 and R2 is O-R3 or S-R4, and R3 and R4 are independently a C1 to C10 alkyl group, such that the C1to C10 alkyl group is non-substituted or subs...
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| creator | CHEN, PING-FAN CHANG, KAII TSAO, NING HUANG, HUNG-YUAN CHANG, WEIUNG LEE, KUN-HSIN HUANG, MIN-HUEI |
| description | A compound represented by formula (I) is provided, wherein in formula (I), R1 and R2 each independently represents hydrogen, O-R3 or S-R4, at least one of R1 and R2 is O-R3 or S-R4, and R3 and R4 are independently a C1 to C10 alkyl group, such that the C1to C10 alkyl group is non-substituted or substituted with at least one selected from the group consisting of -OH, -NH2, halogen, ester, ether, and carboxylic acid, and M being a metal or a metal-containing compound. The compound represented by formula (I) is shown to have higher specificity to tumor cells, and is therefore suitable for carrying anti-cancer drugs and/or nuclear imaging agents. A pharmaceutical composition for tumor imaging and tumor therapy is also provided. formula (I). |
| format | Patent |
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The compound represented by formula (I) is shown to have higher specificity to tumor cells, and is therefore suitable for carrying anti-cancer drugs and/or nuclear imaging agents. A pharmaceutical composition for tumor imaging and tumor therapy is also provided. formula (I).</description><language>chi ; eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; APPARATUS THEREFOR ; CHEMISTRY ; GENERAL METHODS OF ORGANIC CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180411&DB=EPODOC&CC=TW&NR=I620734B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180411&DB=EPODOC&CC=TW&NR=I620734B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHEN, PING-FAN</creatorcontrib><creatorcontrib>CHANG, KAII</creatorcontrib><creatorcontrib>TSAO, NING</creatorcontrib><creatorcontrib>HUANG, HUNG-YUAN</creatorcontrib><creatorcontrib>CHANG, WEIUNG</creatorcontrib><creatorcontrib>LEE, KUN-HSIN</creatorcontrib><creatorcontrib>HUANG, MIN-HUEI</creatorcontrib><title>Compound and pharmaceutical composition for tumor imaging and tumor therapy</title><description>A compound represented by formula (I) is provided, wherein in formula (I), R1 and R2 each independently represents hydrogen, O-R3 or S-R4, at least one of R1 and R2 is O-R3 or S-R4, and R3 and R4 are independently a C1 to C10 alkyl group, such that the C1to C10 alkyl group is non-substituted or substituted with at least one selected from the group consisting of -OH, -NH2, halogen, ester, ether, and carboxylic acid, and M being a metal or a metal-containing compound. 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The compound represented by formula (I) is shown to have higher specificity to tumor cells, and is therefore suitable for carrying anti-cancer drugs and/or nuclear imaging agents. A pharmaceutical composition for tumor imaging and tumor therapy is also provided. formula (I).</abstract><oa>free_for_read</oa></addata></record> |
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| language | chi ; eng |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Compound and pharmaceutical composition for tumor imaging and tumor therapy |
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