Boronic acid bearing liphagane compounds as inhibitors of pi3k-α and/or β

Compounds with unique liphagane meroterpenoid scaffold having boronic acid functionality in the skeleton are described (formula 1) together with pharmacological potential of these compounds as anticancer agents. A method of preparation and inhibiting the activity of phosphoinositide-3-kinase (PI3K-a...

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Hauptverfasser:	VISHWAKARMA, RAM ASREY, DAR, ABID HAMID, SAXENA, AJIT KUMAR, HUSSAIN, AASHIQ, SINGH, PARVINDER PAL, SHARMA, PARDUMAN RAJ, KOLLURU, ANJANEYA ARAVIND KUMAR, QAZI, ASIF KHURSHID, NARGOTRA, AMIT, CHANAURIA, NAYAN, SAWANT, SANGHAPAL DAMODHAR, MUDUDUDDLA, RAMESH
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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