Immunogenic compositions and methods for eliciting an immune response against Clostridioides (clostridium) difficile
The present invention relates to immunogenic compositions that comprise a Clostridioides difficile toxoid A and/or a C. difficile toxoid B, and an adjuvant, and methods of use thereof. The present invention further relate to a methods for eliciting an enhanced immune response in a human against a C....
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| creator | PHELAN, LYNN MARIE PRIDE, MICHAEL WILLIAM SHI, SHUAI SURENDRAN, NAVEEN MORAN, JUSTIN KEITH HU, LEI LIBERATOR, PAUL ARTHUR GONZALEZ-GARIS, MARINA A ANDERSON, ANNALIESA SYBIL KANEVSKY, ISIS |
| description | The present invention relates to immunogenic compositions that comprise a Clostridioides difficile toxoid A and/or a C. difficile toxoid B, and an adjuvant, and methods of use thereof. The present invention further relate to a methods for eliciting an enhanced immune response in a human against a C. difficile infection. The methods include administering to the human an effective dose of an immunogenic composition, which includes a C. difficile toxoid and an adjuvant, wherein the composition is administered two times. |
| format | Patent |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Immunogenic compositions and methods for eliciting an immune response against Clostridioides (clostridium) difficile |
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