Fused pyridazine derivative
The present invention addresses the problem of providing a pharmaceutical composition, particularly a compound that is suitable for preventing and/or treating inflammatory diseases and/or neurodegenerative diseases. The inventors of the present invention conducted extensive studies to find a compoun...
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| creator | TOMIYAMA, HIROSHI KOIZUMI, YUKA NAKAMURA, AKIHIKO TOYA, HIROKI IIKUBO, KAZUHIKO WASHIO, TAKUYA IWAI, YOSHINORI YAMASHITA, YUMI INAGAKI, YUSUKE |
| description | The present invention addresses the problem of providing a pharmaceutical composition, particularly a compound that is suitable for preventing and/or treating inflammatory diseases and/or neurodegenerative diseases. The inventors of the present invention conducted extensive studies to find a compound that has an action for inhibiting activation of NLRP3 inflammasomes and discovered that a fused pyridazine derivative has an action for inhibiting activation of NLRP3 inflammasomes, thereby perfecting the present invention. A fused pyridazine derivative according to the present invention is expected to serve as a drug for preventing and/or treating inflammatory diseases and/or neurodegenerative diseases. |
| format | Patent |
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The inventors of the present invention conducted extensive studies to find a compound that has an action for inhibiting activation of NLRP3 inflammasomes and discovered that a fused pyridazine derivative has an action for inhibiting activation of NLRP3 inflammasomes, thereby perfecting the present invention. 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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Fused pyridazine derivative |
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