Engineered CD200R antibodies and uses thereof

In some aspects, provided herein are antibodies or antigen-binding fragments that bind to CD200R, a glycoprotein receptor present on cell surfaces. Antibodies or antigen-binding fragments provided herein, in some cases, agonize CD200R signaling pathway that inhibits inflammation and immune response....

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Hauptverfasser: DAVIS, SIMON JOHN, MURRAY, LYNNE ANNE, SCOTT, ELEANOR MARYSIA, TOMAZELA, DANIELA M, PALUCH, CHRISTOPHER DOUGLAS, CORNALL, RICHARD JOHN, ROBERTSON, NATHAN JACOB
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creator DAVIS, SIMON JOHN
MURRAY, LYNNE ANNE
SCOTT, ELEANOR MARYSIA
TOMAZELA, DANIELA M
PALUCH, CHRISTOPHER DOUGLAS
CORNALL, RICHARD JOHN
ROBERTSON, NATHAN JACOB
description In some aspects, provided herein are antibodies or antigen-binding fragments that bind to CD200R, a glycoprotein receptor present on cell surfaces. Antibodies or antigen-binding fragments provided herein, in some cases, agonize CD200R signaling pathway that inhibits inflammation and immune response. In other aspects, provided herein are compositions, methods of use, methods of making, polynucleotides, vectors, host cells, and kits relating to antibodies or antigen-binding fragments that bind to CD200R.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title Engineered CD200R antibodies and uses thereof
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