Pyrimidino-dihydropyrazolone-containing derivative, pharmaceutically acceptable salt thereof, preparation method and application of pyrimidino-dihydropyrazolone-containing derivative

The invention discloses a pyrimidino-dihydropyrazolone-containing derivative, a pharmaceutically acceptable salt thereof, and a preparation method and application of the pyrimidino-dihydropyrazolone-containing derivative. The invention provides a pyrimidino-dihydropyrazolone-containing derivative, a...

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Hauptverfasser:	YUAN, HONG-BIN, LIU, KUN CHIN, ZHOU, GUO-QIANG, WEI, YI
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	YUAN, HONG-BIN LIU, KUN CHIN ZHOU, GUO-QIANG WEI, YI
description	The invention discloses a pyrimidino-dihydropyrazolone-containing derivative, a pharmaceutically acceptable salt thereof, and a preparation method and application of the pyrimidino-dihydropyrazolone-containing derivative. The invention provides a pyrimidino-dihydropyrazolone-containing derivative, and a stereoisomer or a pharmaceutically acceptable salt of the pyrimidino-dihydropyrazolone-containing derivative. The compound can inhibit Wee1, has better selectivity to Plk1, and can be used for treating cancers.
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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	Pyrimidino-dihydropyrazolone-containing derivative, pharmaceutically acceptable salt thereof, preparation method and application of pyrimidino-dihydropyrazolone-containing derivative
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