Solid form of diaminopyrimidine compound or hydrate thereof, preparation method therefor, and application thereof

The present invention relates to a solid form of 5-((2-ethynyl-5-isopropylpyridin-4-yl)oxy)pyrimidine-2,4-diamine or a hydrate thereof, a method for preparing the solid form, a pharmaceutical composition comprising the solid form, and a use of the solid form for the prevention or treatment of a dise...

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Hauptverfasser: LIU, KAI, CHENG, CHEUNG-LING, ZHOU, LI-YING, HUANG, HUAI, WANG, HONG-JUN, FU, SHEN-ZHEN, TIAN, NA-NA, CHEN, XIAO, PANG, JIAN-MEI, MENG, JIE, LIU, YA-NAN, ZHAO, YAN-PING, FENG, ZE-WANG, LIU, XUE-LIAN
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creator LIU, KAI
CHENG, CHEUNG-LING
ZHOU, LI-YING
HUANG, HUAI
WANG, HONG-JUN
FU, SHEN-ZHEN
TIAN, NA-NA
CHEN, XIAO
PANG, JIAN-MEI
MENG, JIE
LIU, YA-NAN
ZHAO, YAN-PING
FENG, ZE-WANG
LIU, XUE-LIAN
description The present invention relates to a solid form of 5-((2-ethynyl-5-isopropylpyridin-4-yl)oxy)pyrimidine-2,4-diamine or a hydrate thereof, a method for preparing the solid form, a pharmaceutical composition comprising the solid form, and a use of the solid form for the prevention or treatment of a disease modulated by P2X3 and/or P2X2/3 receptor antagonists.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Solid form of diaminopyrimidine compound or hydrate thereof, preparation method therefor, and application thereof
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