Bicyclic pyrazole bruton's tyrosine kinase inhibitors

The present invention provides for compounds of formula (I); wherein A, R1, R2, R4, W, m, and n have any of the values defined herein, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of CLL and/or SLL.

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: GRESZLER, STEPHEN N, KHRAKOVSKY, DIMITRI, DEANDA, FELIX, WANG, LONGCHENG, SIPPY, KEVIN B, ZABLOCKI, JEFFERY A, DEGOEY, DAVID A, DOMBROWSKI, AMANDA W, DUBOVYK, IGOR, NEWTON, JAMES N, NOEY, ELIZABETH L, OKANO, AKINORI, WILSON, NOEL S, SOUERS, ANDREW J, LEE, CHIH-HUNG
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator GRESZLER, STEPHEN N
KHRAKOVSKY, DIMITRI
DEANDA, FELIX
WANG, LONGCHENG
SIPPY, KEVIN B
ZABLOCKI, JEFFERY A
DEGOEY, DAVID A
DOMBROWSKI, AMANDA W
DUBOVYK, IGOR
NEWTON, JAMES N
NOEY, ELIZABETH L
OKANO, AKINORI
WILSON, NOEL S
SOUERS, ANDREW J
LEE, CHIH-HUNG
description The present invention provides for compounds of formula (I); wherein A, R1, R2, R4, W, m, and n have any of the values defined herein, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of CLL and/or SLL.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_TW202235075A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>TW202235075A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_TW202235075A3</originalsourceid><addsrcrecordid>eNrjZDB1ykyuTM7JTFYoqCxKrMrPSVVIKiotyc9TL1YoqSzKL87MS1XIzsxLLE5VyMzLyEzKLMkvKuZhYE1LzClO5YXS3AyKbq4hzh66qQX58anFBYnJqXmpJfEh4UYGRkbGpgbmpo7GxKgBAKmJLeM</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Bicyclic pyrazole bruton's tyrosine kinase inhibitors</title><source>esp@cenet</source><creator>GRESZLER, STEPHEN N ; KHRAKOVSKY, DIMITRI ; DEANDA, FELIX ; WANG, LONGCHENG ; SIPPY, KEVIN B ; ZABLOCKI, JEFFERY A ; DEGOEY, DAVID A ; DOMBROWSKI, AMANDA W ; DUBOVYK, IGOR ; NEWTON, JAMES N ; NOEY, ELIZABETH L ; OKANO, AKINORI ; WILSON, NOEL S ; SOUERS, ANDREW J ; LEE, CHIH-HUNG</creator><creatorcontrib>GRESZLER, STEPHEN N ; KHRAKOVSKY, DIMITRI ; DEANDA, FELIX ; WANG, LONGCHENG ; SIPPY, KEVIN B ; ZABLOCKI, JEFFERY A ; DEGOEY, DAVID A ; DOMBROWSKI, AMANDA W ; DUBOVYK, IGOR ; NEWTON, JAMES N ; NOEY, ELIZABETH L ; OKANO, AKINORI ; WILSON, NOEL S ; SOUERS, ANDREW J ; LEE, CHIH-HUNG</creatorcontrib><description>The present invention provides for compounds of formula (I); wherein A, R1, R2, R4, W, m, and n have any of the values defined herein, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of CLL and/or SLL.</description><language>chi ; eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20220916&amp;DB=EPODOC&amp;CC=TW&amp;NR=202235075A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20220916&amp;DB=EPODOC&amp;CC=TW&amp;NR=202235075A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GRESZLER, STEPHEN N</creatorcontrib><creatorcontrib>KHRAKOVSKY, DIMITRI</creatorcontrib><creatorcontrib>DEANDA, FELIX</creatorcontrib><creatorcontrib>WANG, LONGCHENG</creatorcontrib><creatorcontrib>SIPPY, KEVIN B</creatorcontrib><creatorcontrib>ZABLOCKI, JEFFERY A</creatorcontrib><creatorcontrib>DEGOEY, DAVID A</creatorcontrib><creatorcontrib>DOMBROWSKI, AMANDA W</creatorcontrib><creatorcontrib>DUBOVYK, IGOR</creatorcontrib><creatorcontrib>NEWTON, JAMES N</creatorcontrib><creatorcontrib>NOEY, ELIZABETH L</creatorcontrib><creatorcontrib>OKANO, AKINORI</creatorcontrib><creatorcontrib>WILSON, NOEL S</creatorcontrib><creatorcontrib>SOUERS, ANDREW J</creatorcontrib><creatorcontrib>LEE, CHIH-HUNG</creatorcontrib><title>Bicyclic pyrazole bruton's tyrosine kinase inhibitors</title><description>The present invention provides for compounds of formula (I); wherein A, R1, R2, R4, W, m, and n have any of the values defined herein, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of CLL and/or SLL.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDB1ykyuTM7JTFYoqCxKrMrPSVVIKiotyc9TL1YoqSzKL87MS1XIzsxLLE5VyMzLyEzKLMkvKuZhYE1LzClO5YXS3AyKbq4hzh66qQX58anFBYnJqXmpJfEh4UYGRkbGpgbmpo7GxKgBAKmJLeM</recordid><startdate>20220916</startdate><enddate>20220916</enddate><creator>GRESZLER, STEPHEN N</creator><creator>KHRAKOVSKY, DIMITRI</creator><creator>DEANDA, FELIX</creator><creator>WANG, LONGCHENG</creator><creator>SIPPY, KEVIN B</creator><creator>ZABLOCKI, JEFFERY A</creator><creator>DEGOEY, DAVID A</creator><creator>DOMBROWSKI, AMANDA W</creator><creator>DUBOVYK, IGOR</creator><creator>NEWTON, JAMES N</creator><creator>NOEY, ELIZABETH L</creator><creator>OKANO, AKINORI</creator><creator>WILSON, NOEL S</creator><creator>SOUERS, ANDREW J</creator><creator>LEE, CHIH-HUNG</creator><scope>EVB</scope></search><sort><creationdate>20220916</creationdate><title>Bicyclic pyrazole bruton's tyrosine kinase inhibitors</title><author>GRESZLER, STEPHEN N ; KHRAKOVSKY, DIMITRI ; DEANDA, FELIX ; WANG, LONGCHENG ; SIPPY, KEVIN B ; ZABLOCKI, JEFFERY A ; DEGOEY, DAVID A ; DOMBROWSKI, AMANDA W ; DUBOVYK, IGOR ; NEWTON, JAMES N ; NOEY, ELIZABETH L ; OKANO, AKINORI ; WILSON, NOEL S ; SOUERS, ANDREW J ; LEE, CHIH-HUNG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_TW202235075A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2022</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>GRESZLER, STEPHEN N</creatorcontrib><creatorcontrib>KHRAKOVSKY, DIMITRI</creatorcontrib><creatorcontrib>DEANDA, FELIX</creatorcontrib><creatorcontrib>WANG, LONGCHENG</creatorcontrib><creatorcontrib>SIPPY, KEVIN B</creatorcontrib><creatorcontrib>ZABLOCKI, JEFFERY A</creatorcontrib><creatorcontrib>DEGOEY, DAVID A</creatorcontrib><creatorcontrib>DOMBROWSKI, AMANDA W</creatorcontrib><creatorcontrib>DUBOVYK, IGOR</creatorcontrib><creatorcontrib>NEWTON, JAMES N</creatorcontrib><creatorcontrib>NOEY, ELIZABETH L</creatorcontrib><creatorcontrib>OKANO, AKINORI</creatorcontrib><creatorcontrib>WILSON, NOEL S</creatorcontrib><creatorcontrib>SOUERS, ANDREW J</creatorcontrib><creatorcontrib>LEE, CHIH-HUNG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GRESZLER, STEPHEN N</au><au>KHRAKOVSKY, DIMITRI</au><au>DEANDA, FELIX</au><au>WANG, LONGCHENG</au><au>SIPPY, KEVIN B</au><au>ZABLOCKI, JEFFERY A</au><au>DEGOEY, DAVID A</au><au>DOMBROWSKI, AMANDA W</au><au>DUBOVYK, IGOR</au><au>NEWTON, JAMES N</au><au>NOEY, ELIZABETH L</au><au>OKANO, AKINORI</au><au>WILSON, NOEL S</au><au>SOUERS, ANDREW J</au><au>LEE, CHIH-HUNG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Bicyclic pyrazole bruton's tyrosine kinase inhibitors</title><date>2022-09-16</date><risdate>2022</risdate><abstract>The present invention provides for compounds of formula (I); wherein A, R1, R2, R4, W, m, and n have any of the values defined herein, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of CLL and/or SLL.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language chi ; eng
recordid cdi_epo_espacenet_TW202235075A
source esp@cenet
subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Bicyclic pyrazole bruton's tyrosine kinase inhibitors
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T05%3A11%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=GRESZLER,%20STEPHEN%20N&rft.date=2022-09-16&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ETW202235075A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true