IL-17A inhibitors

The invention provides certain difluorocyclohexyl-imidazopyridazinyl-imidazolidinone compounds of formula II as IL-17A inhibitors, pharmaceutical compositions thereof, and methods of using a compound of formula II to treat certain symptoms of psoriasis, rheumatoid arthritis or multiple sclerosis.

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Hauptverfasser: HOLLOWAY, WILLIAM GLEN, FRIMPONG, KWAME, WOODMAN, MICHAEL EDWARD, JONES, SPENCER BRIAN, RICHETT, MICHAEL ENRICO, LUGAR, CHARLES WILLIS, COATES, DAVID ANDREW, LEVINSON, ADAM MARC, WATSON, BRIAN MORGAN
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creator HOLLOWAY, WILLIAM GLEN
FRIMPONG, KWAME
WOODMAN, MICHAEL EDWARD
JONES, SPENCER BRIAN
RICHETT, MICHAEL ENRICO
LUGAR, CHARLES WILLIS
COATES, DAVID ANDREW
LEVINSON, ADAM MARC
WATSON, BRIAN MORGAN
description The invention provides certain difluorocyclohexyl-imidazopyridazinyl-imidazolidinone compounds of formula II as IL-17A inhibitors, pharmaceutical compositions thereof, and methods of using a compound of formula II to treat certain symptoms of psoriasis, rheumatoid arthritis or multiple sclerosis.
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language chi ; eng
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title IL-17A inhibitors
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