Processes for preparing JAK inhibitors and related intermediate compounds
The present invention is related to processes for preparing chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines of Formula III, and related synthetic intermediate compounds. The chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines are useful as inhibitors of the Janus Kinase family of protein t...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | chi ; eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | LIU, PING-LI XIA, MICHAEL WANG, HAISHENG LIN, QI-YAN ZHOU, JIACHENG RODGERS, JAMES D MELONI, DAVID YUE, TAI-YUEN PAN, YONGUN METCALF, BRIAN W LI, MEI |
| description | The present invention is related to processes for preparing chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines of Formula III, and related synthetic intermediate compounds. The chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines are useful as inhibitors of the Janus Kinase family of protein tyrosine kinases (JAKs) for treatment of inflammatory diseases, myeloproliferative disorders, and other diseases. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_TW202118766A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>TW202118766A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_TW202118766A3</originalsourceid><addsrcrecordid>eNrjZPAMKMpPTi0uTi1WSMsvUigoSi1ILMrMS1fwcvRWyMzLyEzKLMkvKlZIzEtRKErNSSxJTQEKl6QW5aamZAJ5Csn5uQX5pXkpxTwMrGmJOcWpvFCam0HRzTXE2UM3tSA_PrW4IDE5NS-1JD4k3MjAyNDQwtzMzNGYGDUA_Ow1JA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Processes for preparing JAK inhibitors and related intermediate compounds</title><source>esp@cenet</source><creator>LIU, PING-LI ; XIA, MICHAEL ; WANG, HAISHENG ; LIN, QI-YAN ; ZHOU, JIACHENG ; RODGERS, JAMES D ; MELONI, DAVID ; YUE, TAI-YUEN ; PAN, YONGUN ; METCALF, BRIAN W ; LI, MEI</creator><creatorcontrib>LIU, PING-LI ; XIA, MICHAEL ; WANG, HAISHENG ; LIN, QI-YAN ; ZHOU, JIACHENG ; RODGERS, JAMES D ; MELONI, DAVID ; YUE, TAI-YUEN ; PAN, YONGUN ; METCALF, BRIAN W ; LI, MEI</creatorcontrib><description>The present invention is related to processes for preparing chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines of Formula III, and related synthetic intermediate compounds. The chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines are useful as inhibitors of the Janus Kinase family of protein tyrosine kinases (JAKs) for treatment of inflammatory diseases, myeloproliferative disorders, and other diseases.</description><language>chi ; eng</language><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210516&DB=EPODOC&CC=TW&NR=202118766A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210516&DB=EPODOC&CC=TW&NR=202118766A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LIU, PING-LI</creatorcontrib><creatorcontrib>XIA, MICHAEL</creatorcontrib><creatorcontrib>WANG, HAISHENG</creatorcontrib><creatorcontrib>LIN, QI-YAN</creatorcontrib><creatorcontrib>ZHOU, JIACHENG</creatorcontrib><creatorcontrib>RODGERS, JAMES D</creatorcontrib><creatorcontrib>MELONI, DAVID</creatorcontrib><creatorcontrib>YUE, TAI-YUEN</creatorcontrib><creatorcontrib>PAN, YONGUN</creatorcontrib><creatorcontrib>METCALF, BRIAN W</creatorcontrib><creatorcontrib>LI, MEI</creatorcontrib><title>Processes for preparing JAK inhibitors and related intermediate compounds</title><description>The present invention is related to processes for preparing chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines of Formula III, and related synthetic intermediate compounds. The chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines are useful as inhibitors of the Janus Kinase family of protein tyrosine kinases (JAKs) for treatment of inflammatory diseases, myeloproliferative disorders, and other diseases.</description><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPAMKMpPTi0uTi1WSMsvUigoSi1ILMrMS1fwcvRWyMzLyEzKLMkvKlZIzEtRKErNSSxJTQEKl6QW5aamZAJ5Csn5uQX5pXkpxTwMrGmJOcWpvFCam0HRzTXE2UM3tSA_PrW4IDE5NS-1JD4k3MjAyNDQwtzMzNGYGDUA_Ow1JA</recordid><startdate>20210516</startdate><enddate>20210516</enddate><creator>LIU, PING-LI</creator><creator>XIA, MICHAEL</creator><creator>WANG, HAISHENG</creator><creator>LIN, QI-YAN</creator><creator>ZHOU, JIACHENG</creator><creator>RODGERS, JAMES D</creator><creator>MELONI, DAVID</creator><creator>YUE, TAI-YUEN</creator><creator>PAN, YONGUN</creator><creator>METCALF, BRIAN W</creator><creator>LI, MEI</creator><scope>EVB</scope></search><sort><creationdate>20210516</creationdate><title>Processes for preparing JAK inhibitors and related intermediate compounds</title><author>LIU, PING-LI ; XIA, MICHAEL ; WANG, HAISHENG ; LIN, QI-YAN ; ZHOU, JIACHENG ; RODGERS, JAMES D ; MELONI, DAVID ; YUE, TAI-YUEN ; PAN, YONGUN ; METCALF, BRIAN W ; LI, MEI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_TW202118766A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2021</creationdate><topic>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>LIU, PING-LI</creatorcontrib><creatorcontrib>XIA, MICHAEL</creatorcontrib><creatorcontrib>WANG, HAISHENG</creatorcontrib><creatorcontrib>LIN, QI-YAN</creatorcontrib><creatorcontrib>ZHOU, JIACHENG</creatorcontrib><creatorcontrib>RODGERS, JAMES D</creatorcontrib><creatorcontrib>MELONI, DAVID</creatorcontrib><creatorcontrib>YUE, TAI-YUEN</creatorcontrib><creatorcontrib>PAN, YONGUN</creatorcontrib><creatorcontrib>METCALF, BRIAN W</creatorcontrib><creatorcontrib>LI, MEI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LIU, PING-LI</au><au>XIA, MICHAEL</au><au>WANG, HAISHENG</au><au>LIN, QI-YAN</au><au>ZHOU, JIACHENG</au><au>RODGERS, JAMES D</au><au>MELONI, DAVID</au><au>YUE, TAI-YUEN</au><au>PAN, YONGUN</au><au>METCALF, BRIAN W</au><au>LI, MEI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Processes for preparing JAK inhibitors and related intermediate compounds</title><date>2021-05-16</date><risdate>2021</risdate><abstract>The present invention is related to processes for preparing chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines of Formula III, and related synthetic intermediate compounds. The chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines are useful as inhibitors of the Janus Kinase family of protein tyrosine kinases (JAKs) for treatment of inflammatory diseases, myeloproliferative disorders, and other diseases.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | chi ; eng |
| recordid | cdi_epo_espacenet_TW202118766A |
| source | esp@cenet |
| subjects | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
| title | Processes for preparing JAK inhibitors and related intermediate compounds |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T14%3A26%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=LIU,%20PING-LI&rft.date=2021-05-16&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ETW202118766A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |