Fused ring compound having urea structure

The present invention relates to a novel fused ring compound having urea structure that exhibits excellent NAMPT activating effect, and a method using the same for treating / preventing metabolic disorder, cardiovascular and kidney disease, mitochondrial disease, neurodegenerative disease, ocular di...

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Hauptverfasser: TSUJI, TAKASHI, NAKAMURA, TSUYOSHI, TERAYAMA, KOJI, TANAKA, JUN, AKIU, MAYUKO, YOKOYAMA, MIKA, PINKERTON, ANTHONY B, SESSIONS, EDWARD HAMPTON
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creator TSUJI, TAKASHI
NAKAMURA, TSUYOSHI
TERAYAMA, KOJI
TANAKA, JUN
AKIU, MAYUKO
YOKOYAMA, MIKA
PINKERTON, ANTHONY B
SESSIONS, EDWARD HAMPTON
description The present invention relates to a novel fused ring compound having urea structure that exhibits excellent NAMPT activating effect, and a method using the same for treating / preventing metabolic disorder, cardiovascular and kidney disease, mitochondrial disease, neurodegenerative disease, ocular disease, and muscle wasting disorder. The present invention provides a compound represented by following formula (I) or a pharmacologically acceptable salt: wherein A, B, R1, R2 and R3 represent the same meanings as in the claims.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Fused ring compound having urea structure
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