Bicyclic compound and use thereof for inhibiting histone methyltransferase

The present invention relates to a compound represented by formula (I), a method for the preparation thereof, and a pharmaceutical composition containing the compound as an active ingredient for inhibiting histone methyltransferase such as SUV39H2.

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Hauptverfasser: RAVULA, SRINIVAS, DUAN, ZHI-YONG, NAKAMURA, YUSUKE, MIYAMOTO, TAKASHI, CHAKRABARTI, ANJAN, MATSUO, YO, DUPATI, PRAVEEN, MANTIPALLY, MANOHAR, SIVALENKA, VIJAYASARADHI, PATNAIK, PRAVEEN, OKAMOTO, YASUHIDE
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creator RAVULA, SRINIVAS
DUAN, ZHI-YONG
NAKAMURA, YUSUKE
MIYAMOTO, TAKASHI
CHAKRABARTI, ANJAN
MATSUO, YO
DUPATI, PRAVEEN
MANTIPALLY, MANOHAR
SIVALENKA, VIJAYASARADHI
PATNAIK, PRAVEEN
OKAMOTO, YASUHIDE
description The present invention relates to a compound represented by formula (I), a method for the preparation thereof, and a pharmaceutical composition containing the compound as an active ingredient for inhibiting histone methyltransferase such as SUV39H2.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Bicyclic compound and use thereof for inhibiting histone methyltransferase
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