Method for producing epirubicin and novel production intermediate therefor

Method for producing epirubicin and novel production intermediate therefor

In the present invention, an organic acid salt of 4'-epidaunorubicin or a hydrate or a solvate thereof is used as a novel production intermediate, whereby it is possible to efficiently remove 13-dihydroepidaunorubicin and 4'-epifeudomycin, which are typical impurities that may be present i...

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Hauptverfasser: MARUYAMA, TAKAHISA, SHIOKAWA, SOJIRO, MORI, KENICHIRO, UMEZU, TAKUTO
Format: Patent
Sprache:chi ; eng
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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creator MARUYAMA, TAKAHISA
SHIOKAWA, SOJIRO
MORI, KENICHIRO
UMEZU, TAKUTO
description In the present invention, an organic acid salt of 4'-epidaunorubicin or a hydrate or a solvate thereof is used as a novel production intermediate, whereby it is possible to efficiently remove 13-dihydroepidaunorubicin and 4'-epifeudomycin, which are typical impurities that may be present in the starting-material 4'-epidaunorubicin, and to produce highly pure epirubicin.
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subjects CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
title Method for producing epirubicin and novel production intermediate therefor
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