Novel vaccine compositions for porcine epidemic diarrhea virus and porcine deltacoronavirus

The present invention is directed to novel immunogenic compositions that protect swine from disease caused by porcine epidemic diarrhea virus (PEDV). The present invention is also directed to novel immunogenic compositions that protect swine from disease caused by porcine deltacoronavirus (PDCoV), a...

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Hauptverfasser: DOMINOWSKI, PAUL JOSEPH, PLAJA DILME, LAIA, BALASCH SANUY, MONICA, ROMERO GALINDO, OSCAR, CABANA SUMSI, MARTA, RAPP GABRIELSON, VICKI JON, URNIZA HOSTENCH, ALICIA, MARX, JACQUELINE GAYLE, HARDHAM, JOHN MORGAN
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creator DOMINOWSKI, PAUL JOSEPH
PLAJA DILME, LAIA
BALASCH SANUY, MONICA
ROMERO GALINDO, OSCAR
CABANA SUMSI, MARTA
RAPP GABRIELSON, VICKI JON
URNIZA HOSTENCH, ALICIA
MARX, JACQUELINE GAYLE
HARDHAM, JOHN MORGAN
description The present invention is directed to novel immunogenic compositions that protect swine from disease caused by porcine epidemic diarrhea virus (PEDV). The present invention is also directed to novel immunogenic compositions that protect swine from disease caused by porcine deltacoronavirus (PDCoV), alone or as combination vaccine to protect against PEDV. The compositions of the invention provide killed viruses whose effectiveness is enhanced by the selection of preferred adjuvants. Novel culture methods are also employed to increase reproducible yield of cultured viruses. Live vaccines are also provided from the Calaf14 PEDV isolate.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Novel vaccine compositions for porcine epidemic diarrhea virus and porcine deltacoronavirus
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