2-arylnaphthyridin-4-ones as potent antitumor agents targeting tumorigenic cell lines

In order to search for new antitumor drug candidates from 2-arylnaphthyridin-4-ones (ANs), we have designed and synthesized a series of 3'-hydroxy or 6-hydroxy derivatives of ANs. Following the antitumor activity screening, most of these compounds were found to exhibit significant activity. Amo...

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Hauptverfasser:	LEE, KUO-HSIUNG, CHOU, LIN, CHANG, LINGU, HUANG, CHI-HUNG, TENG, CHE-MING, CHENG, YUNG-YI, HSU, MEI-HUA, HUANG, LI-JIAU, WU, TIAN-SHUNG, TSAI, MENG-TUNG, LIAO, CHIHANG, LIN, HUI-YI, LIU, CHIN-YU, WAY, TZONG-DER, KUO, SHENGU
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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