Substituted pyrimidines as prostaglandin D2 receptor antagonists

The present invention is directed to a substituted pyrimidine compound of formula (I) or an enantiomer thereof, or a prodrug or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising such a compound. The invention also includes a method of treatment of a patient by th...

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Hauptverfasser: AGUIAR, JOACY C, SHUM, PATRICK WAI-KWOK, ZHAO, ZHICHENG, HARRIS, KEITH JOHN, CHOI-SLEDESKI, YONG-MI, REILING, STEPHAN, GARDNER, CHARLES, POLI, GREGORY BERNARD, STOKLOSA, GREGORY, STEFANY, DAVID
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention is directed to a substituted pyrimidine compound of formula (I) or an enantiomer thereof, or a prodrug or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising such a compound. The invention also includes a method of treatment of a patient by the administration of a pharmaceutically effective amount of such a compound.