Integrin antagonists useful as anticancer agents

Integrin antagonists useful as anticancer agents

The invention relates to compounds of the Formula 1, and to pharmaceutically acceptable salts and solvates thereof, wherein A, X2, X4, X5 and X1 are as defined herein. The invention also relates to methods of treating abnormal cell growth in mammals by administering the compounds of Formula 1 and to...

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Hauptverfasser: WYNNE, GRAHAM M, COLLINGTON, ERIC WILLIAM, SAMBROOK SMITH, COLIN PETER, BORZILLO, GARY V, SADIQ, SHAZIA, BLOXHAM, JASON, WALLER, CHRIS L
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creator WYNNE, GRAHAM M
COLLINGTON, ERIC WILLIAM
SAMBROOK SMITH, COLIN PETER
BORZILLO, GARY V
SADIQ, SHAZIA
BLOXHAM, JASON
WALLER, CHRIS L
description The invention relates to compounds of the Formula 1, and to pharmaceutically acceptable salts and solvates thereof, wherein A, X2, X4, X5 and X1 are as defined herein. The invention also relates to methods of treating abnormal cell growth in mammals by administering the compounds of Formula 1 and to pharmaceutical compositions for treating such disorders which contain the compounds of Formula 1.
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title Integrin antagonists useful as anticancer agents
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