Novel inhibitors of DPP-IV, methods of preparing the same, and pharmaceutical compositions containing the same as an active agent

The present invention relates to pyrrolidine-based compounds of novel structure exhibiting good inhibitory activity versus Dipeptidyl Peptidase-IV, and methods of preparing the same and pharmaceutical compositions containing the same as an active agent, wherein A, B, R1, R2, R3, and Y are the same a...

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Hauptverfasser: KIM, SUNG-SUB, KIM, DONG-MYUNG, KIM, SUNGHO, CHUNG, HEE-KYUNG, LEE, CHANG-SEOK, KIM, KYOUNG-HEE, KWON, TAE-SIK, HAN, HEE-OON, KIM, BONGCHAN, KIM, YEONUL, LEE, HEE-BONG, LIM, DONGCHUL, YOON, SUK-KYOON, KIM, SUNGJI, HUR, GWONGUNG, LEE, SUN-HWA, KIM, GEUN-TAE, KIM, MISUN, KOH, JONG-SUNG, KWON, OH-HWAN, KIM, MIN-JUNG, KOO, KI-DONG, YIM, HYEON-JOO
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Sprache:chi ; eng
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creator KIM, SUNG-SUB
KIM, DONG-MYUNG
KIM, SUNGHO
CHUNG, HEE-KYUNG
LEE, CHANG-SEOK
KIM, KYOUNG-HEE
KWON, TAE-SIK
HAN, HEE-OON
KIM, BONGCHAN
KIM, YEONUL
LEE, HEE-BONG
LIM, DONGCHUL
YOON, SUK-KYOON
KIM, SUNGJI
HUR, GWONGUNG
LEE, SUN-HWA
KIM, GEUN-TAE
KIM, MISUN
KOH, JONG-SUNG
KWON, OH-HWAN
KIM, MIN-JUNG
KOO, KI-DONG
YIM, HYEON-JOO
description The present invention relates to pyrrolidine-based compounds of novel structure exhibiting good inhibitory activity versus Dipeptidyl Peptidase-IV, and methods of preparing the same and pharmaceutical compositions containing the same as an active agent, wherein A, B, R1, R2, R3, and Y are the same as defined as in description.
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language chi ; eng
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Novel inhibitors of DPP-IV, methods of preparing the same, and pharmaceutical compositions containing the same as an active agent
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