DERIVES DE 2-(2-OXO-ETHYLIDENE)-IMIDAZOLIDINE-4-ONE, PROCEDE POUR LEUR PREPARATION ET COMPOSITIONS PHARMACEUTIQUES LES CONTENANT

L' INVENTION CONCERNE DES COMPOSES DE FORMULE (1): DANS LAQUELLE R1, R2, R3 ET R4, REPRESENTENT DIVERS RADICAUX ORGANIQUES. ELLE CONCERNE EGALEMENT DES PROCEDES POUR LEUR PREPARATION AINSI QUE DES COMPOSITIONS PHARMACEUTIQUES LE CONTENANT.APPLICATION : ADMINISTRATION DE CES COMPOSES ET COMPOSIT...

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1. Verfasser:	JOSEPH PETER LYSSIKATOS
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Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	JOSEPH PETER LYSSIKATOS
description	L' INVENTION CONCERNE DES COMPOSES DE FORMULE (1): DANS LAQUELLE R1, R2, R3 ET R4, REPRESENTENT DIVERS RADICAUX ORGANIQUES. ELLE CONCERNE EGALEMENT DES PROCEDES POUR LEUR PREPARATION AINSI QUE DES COMPOSITIONS PHARMACEUTIQUES LE CONTENANT.APPLICATION : ADMINISTRATION DE CES COMPOSES ET COMPOSITIONS POUR INHIBER UNE CROISSANCE CELLULAIRE ANORMALE CHEZ UN MAMMIFERE PCT No. PCT/IB97/00584 Sec. 371 Date Oct. 7, 1999 Sec. 102(e) Date Oct. 7, 1999 PCT Filed May 22, 1997 PCT Pub. No. WO97/49700 PCT Pub. Date Dec. 31, 1997The present invention relates to compounds of the formula wherein R1, R2, R3 and R4 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula I and to methods of inhibiting abnormal cell growth, including cancer, in a mammal by administering the compounds of formula I to said mammal.
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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	DERIVES DE 2-(2-OXO-ETHYLIDENE)-IMIDAZOLIDINE-4-ONE, PROCEDE POUR LEUR PREPARATION ET COMPOSITIONS PHARMACEUTIQUES LES CONTENANT
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