DUAL FUNCTION PROTEINS FOR TREATING METABOLIC DISORDERS

The present invention relates to the identification of new proteins comprising fibroblast growth factor 21 (FGF21) and other metabolic regulators, including variants thereof, known to improve metabolic profiles in subjects to whom they are administered. Also disclosed are methods for treating FGF21-...

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Bibliographische Detailangaben
Hauptverfasser: WELDON STEPHEN CRAIG, LICHT STUART, BOETTCHER BRIAN R, CAPLAN SHARI L, HAMAMATSU NORIO, CELLITTI SUSAN E, GEIERSTANGER BERNHARD HUBERT, LOEW ANDREAS, DANIELS DOUGLAS S
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to the identification of new proteins comprising fibroblast growth factor 21 (FGF21) and other metabolic regulators, including variants thereof, known to improve metabolic profiles in subjects to whom they are administered. Also disclosed are methods for treating FGF21-associated disorders, GLP-1-associated disorders, and Exendin-4-associated disorders, including metabolic conditions.