METHOD OF PREPARING ANTHRACYCLINE-GLYCOSIDES

Disclosed is a new class of antitumor glycoside antibiotics of the formula (IA): (IA) wherein R is hydrogen or hydroxy; and X is These compounds are prepared, using novel intermediates, by condensing the appropriate aglycone and amino-deoxy sugar to form the alpha -glycosidic linkage.

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Hauptverfasser: FEDERIKO ARKAMONE,IT, DZHUZEPPE KASSINELLI,IT, AURELIOMARKO,IT
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creator FEDERIKO ARKAMONE,IT
DZHUZEPPE KASSINELLI,IT
AURELIOMARKO,IT
description Disclosed is a new class of antitumor glycoside antibiotics of the formula (IA): (IA) wherein R is hydrogen or hydroxy; and X is These compounds are prepared, using novel intermediates, by condensing the appropriate aglycone and amino-deoxy sugar to form the alpha -glycosidic linkage.
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subjects CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
title METHOD OF PREPARING ANTHRACYCLINE-GLYCOSIDES
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