METHOD OF PREPARING 4-ACYLAMINOPHENYLATHANOLAMINES OR THEIR SALTS
Compounds of the formula wherein R1 is hydrogen, halogen or cyano; R2 is fluorine, cyano, trifluoromethyl, nitro or alkyl of 1 to 4 carbon atoms; R3 is alkoxy of 1 to 5 carbon atoms, alkenyloxy of 2 to 5 carbon atoms, aryloxy of 6 to 10 carbon atoms, aralkoxy of 7 to 11 carbon atoms, or -NR5R6, wher...
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| creator | IOGANNES KEKK,DT GERD KRYUGER,DT GYUNTER ENGELKHARDT,DT GELMUT PIPER,DT KLAUS NOLL,DT |
| description | Compounds of the formula wherein R1 is hydrogen, halogen or cyano; R2 is fluorine, cyano, trifluoromethyl, nitro or alkyl of 1 to 4 carbon atoms; R3 is alkoxy of 1 to 5 carbon atoms, alkenyloxy of 2 to 5 carbon atoms, aryloxy of 6 to 10 carbon atoms, aralkoxy of 7 to 11 carbon atoms, or -NR5R6, where R5 and R6 are each hydrogen, alkyl of 1 to 5 carbon atoms, alkenyl of 2 to 5 carbon atoms, aryl of 6 to 10 carbon atoms or aralkyl of 7 to 11 carbon atoms; and R4 is cycloalkyl of 3 to 5 carbon atoms or alkyl of 3 to 5 carbon atoms; and non-toxic, pharmacologically acceptable acid addition salt thereof. The compounds as well as the salts are useful as analgesics, uterospasmolytics and antiasthmatics. |
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The compounds as well as the salts are useful as analgesics, uterospasmolytics and antiasthmatics.</description><language>eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1979</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19791215&DB=EPODOC&CC=SU&NR=704453A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19791215&DB=EPODOC&CC=SU&NR=704453A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>IOGANNES KEKK,DT</creatorcontrib><creatorcontrib>GERD KRYUGER,DT</creatorcontrib><creatorcontrib>GYUNTER ENGELKHARDT,DT</creatorcontrib><creatorcontrib>GELMUT PIPER,DT</creatorcontrib><creatorcontrib>KLAUS NOLL,DT</creatorcontrib><title>METHOD OF PREPARING 4-ACYLAMINOPHENYLATHANOLAMINES OR THEIR SALTS</title><description>Compounds of the formula wherein R1 is hydrogen, halogen or cyano; R2 is fluorine, cyano, trifluoromethyl, nitro or alkyl of 1 to 4 carbon atoms; R3 is alkoxy of 1 to 5 carbon atoms, alkenyloxy of 2 to 5 carbon atoms, aryloxy of 6 to 10 carbon atoms, aralkoxy of 7 to 11 carbon atoms, or -NR5R6, where R5 and R6 are each hydrogen, alkyl of 1 to 5 carbon atoms, alkenyl of 2 to 5 carbon atoms, aryl of 6 to 10 carbon atoms or aralkyl of 7 to 11 carbon atoms; and R4 is cycloalkyl of 3 to 5 carbon atoms or alkyl of 3 to 5 carbon atoms; and non-toxic, pharmacologically acceptable acid addition salt thereof. 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The compounds as well as the salts are useful as analgesics, uterospasmolytics and antiasthmatics.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | METHOD OF PREPARING 4-ACYLAMINOPHENYLATHANOLAMINES OR THEIR SALTS |
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