METHOD OF OBTAINING AMINOIMIDAZOISOQUINOLINES OR THEIR SALTS

The novel aminopyrazoloisoquinoline derivatives of the formula in which A denotes an alkoxy group containing 1 to 4 carbon atoms and D denotes hydrogen, acyl, alkyl or aralkyl, have a favourable effect on the activity of the heart. They are prepared by treating compounds of the general formula in wh...

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Hauptverfasser: LASLO SEKERESH,HU, ANDRASH NESMELI,HU, KALMAN TAKACH,HU, EVA BENEDEK,HU, KALMAN KHARSHANI,HU, DYULA PAPP,HU
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creator LASLO SEKERESH,HU
ANDRASH NESMELI,HU
KALMAN TAKACH,HU
EVA BENEDEK,HU
KALMAN KHARSHANI,HU
DYULA PAPP,HU
description The novel aminopyrazoloisoquinoline derivatives of the formula in which A denotes an alkoxy group containing 1 to 4 carbon atoms and D denotes hydrogen, acyl, alkyl or aralkyl, have a favourable effect on the activity of the heart. They are prepared by treating compounds of the general formula in which A has the above meaning and R denotes an alkyl, aralkyl or aryl group, with a strong alkaline solution. Compounds of the formula I are thus obtained, in which D denotes hydrogen which can be replaced by an acyl group. This hydrogen can also be replaced by an alkyl or aralkyl group by reaction with an aldehyde or ketone and subsequent reduction of the resulting intermediate.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title METHOD OF OBTAINING AMINOIMIDAZOISOQUINOLINES OR THEIR SALTS
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