METHOD OF OBTAINING DERIVATIVES OF PHENEM OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS
There are provided compounds of formula I :whereinR' is hydrogen or a C1-C4 alkyl group either unsubstituted or substituted by one or more substituents chosen from a free or protected hydroxy or halogen atom;R2 is a free or esterified carboxy group or carboxylate anion;R3 and R4 are each indepe...
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creator | MARKO ALPEDZHANI,IT FRANKO ZARINI,IT KONSTANTINO DELLA BRUNA,IT DZHOVANNI FRANCHESKI,IT ETTORE PERRONE,IT ANDZHELO BEDESKI,IT |
description | There are provided compounds of formula I :whereinR' is hydrogen or a C1-C4 alkyl group either unsubstituted or substituted by one or more substituents chosen from a free or protected hydroxy or halogen atom;R2 is a free or esterified carboxy group or carboxylate anion;R3 and R4 are each independently hydrogen or organic group,X is,-S-,Q is either(a") free or protected hydroxy, or(b") a C1-C4 acyloxy, or(c") carbamoyloxy OCONH2, or(d") an optionally substituted heterocyclylthio group, or(e") an optionally substituted imido group, or(f") an optionally substituted quaternary ammonium group or(g") a halogen atom, and the pharmaceutically or veterinarily acceptable salts thereof.There are provided also methods for preparing compounds of formula 1. The compounds of formula I are useful as antibacterial agents. |
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The compounds of formula I are useful as antibacterial agents.</description><language>eng ; rus</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1990</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19900715&DB=EPODOC&CC=SU&NR=1579461A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25551,76302</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19900715&DB=EPODOC&CC=SU&NR=1579461A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MARKO ALPEDZHANI,IT</creatorcontrib><creatorcontrib>FRANKO ZARINI,IT</creatorcontrib><creatorcontrib>KONSTANTINO DELLA BRUNA,IT</creatorcontrib><creatorcontrib>DZHOVANNI FRANCHESKI,IT</creatorcontrib><creatorcontrib>ETTORE PERRONE,IT</creatorcontrib><creatorcontrib>ANDZHELO BEDESKI,IT</creatorcontrib><title>METHOD OF OBTAINING DERIVATIVES OF PHENEM OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS</title><description>There are provided compounds of formula I :whereinR' is hydrogen or a C1-C4 alkyl group either unsubstituted or substituted by one or more substituents chosen from a free or protected hydroxy or halogen atom;R2 is a free or esterified carboxy group or carboxylate anion;R3 and R4 are each independently hydrogen or organic group,X is,-S-,Q is either(a") free or protected hydroxy, or(b") a C1-C4 acyloxy, or(c") carbamoyloxy OCONH2, or(d") an optionally substituted heterocyclylthio group, or(e") an optionally substituted imido group, or(f") an optionally substituted quaternary ammonium group or(g") a halogen atom, and the pharmaceutically or veterinarily acceptable salts thereof.There are provided also methods for preparing compounds of formula 1. The compounds of formula I are useful as antibacterial agents.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1990</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNiksKwjAQQLNxIeod5gIuSv3gcppOzUA-JZkWXJUicSVaqPdHBQ_g6vF4b6nEkZhQQ2ggVILs2Z-hpsg9CveUvqE15MlBiCCGOH4co0NNnbBGay-AWlMrWFmChFbSWi1u433Omx9XChoSbbZ5eg55nsZrfuTXkLpifzztDgWW5R_LG85vL-g</recordid><startdate>19900715</startdate><enddate>19900715</enddate><creator>MARKO ALPEDZHANI,IT</creator><creator>FRANKO ZARINI,IT</creator><creator>KONSTANTINO DELLA BRUNA,IT</creator><creator>DZHOVANNI FRANCHESKI,IT</creator><creator>ETTORE PERRONE,IT</creator><creator>ANDZHELO BEDESKI,IT</creator><scope>EVB</scope></search><sort><creationdate>19900715</creationdate><title>METHOD OF OBTAINING DERIVATIVES OF PHENEM OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS</title><author>MARKO ALPEDZHANI,IT ; FRANKO ZARINI,IT ; KONSTANTINO DELLA BRUNA,IT ; DZHOVANNI FRANCHESKI,IT ; ETTORE PERRONE,IT ; ANDZHELO BEDESKI,IT</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_SU1579461A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; rus</language><creationdate>1990</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>MARKO ALPEDZHANI,IT</creatorcontrib><creatorcontrib>FRANKO ZARINI,IT</creatorcontrib><creatorcontrib>KONSTANTINO DELLA BRUNA,IT</creatorcontrib><creatorcontrib>DZHOVANNI FRANCHESKI,IT</creatorcontrib><creatorcontrib>ETTORE PERRONE,IT</creatorcontrib><creatorcontrib>ANDZHELO BEDESKI,IT</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MARKO ALPEDZHANI,IT</au><au>FRANKO ZARINI,IT</au><au>KONSTANTINO DELLA BRUNA,IT</au><au>DZHOVANNI FRANCHESKI,IT</au><au>ETTORE PERRONE,IT</au><au>ANDZHELO BEDESKI,IT</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD OF OBTAINING DERIVATIVES OF PHENEM OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS</title><date>1990-07-15</date><risdate>1990</risdate><abstract>There are provided compounds of formula I :whereinR' is hydrogen or a C1-C4 alkyl group either unsubstituted or substituted by one or more substituents chosen from a free or protected hydroxy or halogen atom;R2 is a free or esterified carboxy group or carboxylate anion;R3 and R4 are each independently hydrogen or organic group,X is,-S-,Q is either(a") free or protected hydroxy, or(b") a C1-C4 acyloxy, or(c") carbamoyloxy OCONH2, or(d") an optionally substituted heterocyclylthio group, or(e") an optionally substituted imido group, or(f") an optionally substituted quaternary ammonium group or(g") a halogen atom, and the pharmaceutically or veterinarily acceptable salts thereof.There are provided also methods for preparing compounds of formula 1. The compounds of formula I are useful as antibacterial agents.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | METHOD OF OBTAINING DERIVATIVES OF PHENEM OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS |
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