Process for resolution of enantiomeric mixture

A process for the resolution of an enantiomeric mixture of 1-amino-2-vinylcyclopropyl carboxylic acid methyl ester or an N-protected mixture thereof, comprising the step of treating said mixture with an esterase of subtilisin Bacillus licheniformis (Alcalase) to obtain a desired enantiomer of 1-amin...

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Bibliographische Detailangaben
Hauptverfasser:	HALMOS TEDDY, TSANTRIZOS YOULA S, WERNIC DOMINIK M, CAMERON DALE, GOUDREAU NATHALIE, POUPART MARC-ANDRE, LLINAS-BRUNET MONTSE, BAILEY MURRAY D, FAUCHER ANNE-MARIE, RANCOURT JEAN, GHIRO ELISE
Format:	Patent
Sprache:	eng ; slo
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	A process for the resolution of an enantiomeric mixture of 1-amino-2-vinylcyclopropyl carboxylic acid methyl ester or an N-protected mixture thereof, comprising the step of treating said mixture with an esterase of subtilisin Bacillus licheniformis (Alcalase) to obtain a desired enantiomer of 1-amino-2-vinylcyclopropyl carboxylic acid methyl ester or the N-protected form thereof. A process for the resolution of an enantiomeric mixture of 1-amino-2-vinylcyclopropyl carboxylic acid methyl ester or an N-protected mixture thereof, comprising the step of treating said mixture with an esterase of subtilisin Bacillus licheniformis (Alcalase) to obtain a desired enantiomer of 1-amino-2-vinylcyclopropyl carboxylic acid methyl ester or the N-protected form thereof.