Drospirenone for hormone replacement therapy
A pharmaceutical composition comprising as a first active ingredient an estrogen, such as estradiol or estradiol valerate, in sufficient amounts to treat disorders and symptoms associated with deficient endogenous levels of estrogen in women, and as a second active ingredient 6 beta , 7 beta ; 15 be...
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| creator | LIPP RALPH HEIL WOLFGANG HILMANN JURGEN SCHURMANN ROLF |
| description | A pharmaceutical composition comprising as a first active ingredient an estrogen, such as estradiol or estradiol valerate, in sufficient amounts to treat disorders and symptoms associated with deficient endogenous levels of estrogen in women, and as a second active ingredient 6 beta , 7 beta ; 15 beta ; 16 beta -dimethylene-3-oxo-17 alpha -preg-4-ene-21, 17-carbolactone (drospirenone, DRSP) in sufficient amounts to protect the endometrium from the adverse effects of estrogen. The pharmaceutical composition is useful for treating peri-menopausal, menopausal and post-menopausal women, it may be used for hormone replacement therapy and may be administered as a multi-phased pharmaceutical preparation. This combination therapy may comprise continuous, sequential or interrupted administration, or combinations thereof, of DRSP and estrogen, where each of the active ingredients may be optionally administered in micronized form. |
| format | Patent |
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The pharmaceutical composition is useful for treating peri-menopausal, menopausal and post-menopausal women, it may be used for hormone replacement therapy and may be administered as a multi-phased pharmaceutical preparation. This combination therapy may comprise continuous, sequential or interrupted administration, or combinations thereof, of DRSP and estrogen, where each of the active ingredients may be optionally administered in micronized form.</description><language>eng</language><subject>BABY COMFORTERS ; CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICALPURPOSES ; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY ; DEVICES FOR RECEIVING SPITTLE ; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGINGPHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL ORADMINISTERING FORMS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2011</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110706&DB=EPODOC&CC=SK&NR=287719B6$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110706&DB=EPODOC&CC=SK&NR=287719B6$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LIPP RALPH</creatorcontrib><creatorcontrib>HEIL WOLFGANG</creatorcontrib><creatorcontrib>HILMANN JURGEN</creatorcontrib><creatorcontrib>SCHURMANN ROLF</creatorcontrib><title>Drospirenone for hormone replacement therapy</title><description>A pharmaceutical composition comprising as a first active ingredient an estrogen, such as estradiol or estradiol valerate, in sufficient amounts to treat disorders and symptoms associated with deficient endogenous levels of estrogen in women, and as a second active ingredient 6 beta , 7 beta ; 15 beta ; 16 beta -dimethylene-3-oxo-17 alpha -preg-4-ene-21, 17-carbolactone (drospirenone, DRSP) in sufficient amounts to protect the endometrium from the adverse effects of estrogen. The pharmaceutical composition is useful for treating peri-menopausal, menopausal and post-menopausal women, it may be used for hormone replacement therapy and may be administered as a multi-phased pharmaceutical preparation. 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The pharmaceutical composition is useful for treating peri-menopausal, menopausal and post-menopausal women, it may be used for hormone replacement therapy and may be administered as a multi-phased pharmaceutical preparation. This combination therapy may comprise continuous, sequential or interrupted administration, or combinations thereof, of DRSP and estrogen, where each of the active ingredients may be optionally administered in micronized form.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BABY COMFORTERS CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICALPURPOSES DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY DEVICES FOR RECEIVING SPITTLE DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGINGPHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL ORADMINISTERING FORMS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Drospirenone for hormone replacement therapy |
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