Process for stepwise attachment of polyethylene glycol moieties and use of PEG-polypeptide conjugates produced by this process

Described is a process for stepwise attachment of two or more PEG moieties to a polypeptide and use of the PEG-polypeptide conjugates produced by this method for the production of medicament for the treatment, prognosis or diagnosis of bacterial infections, viral infections, autoimmune diseases and...

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Bibliographische Detailangaben
Hauptverfasser:	ROBERTS MICHAEL J, SAWLIVICH WAYNE, EL TAYAR NABIL, HARRIS MILTON
Format:	Patent
Sprache:	eng ; slo
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Described is a process for stepwise attachment of two or more PEG moieties to a polypeptide and use of the PEG-polypeptide conjugates produced by this method for the production of medicament for the treatment, prognosis or diagnosis of bacterial infections, viral infections, autoimmune diseases and inflammatory diseases. Je opísaný spôsob postupného pripájania dvoch alebo viacerých PEG častí na polypeptid a použitie takto vyrobených PEG-polypeptidových konjugátov na výrobu liečiva na liečbu, profylaxiu alebo diagnostiku bakteriálnych infekcií, vírusových infekcií, autoimunitných ochorení a zápalových ochorení.