Pharmaceutical composition containing ciprofloxacin and method for the preparation thereof

Immediate release pharmaceutical composition contains ciprofloxacin, a binder, disintegrant agent and optionally further pharmaceutical auxiliary agents, namely related to the total weight of the composition 60 - 80 % by weight of ciprofloxacin (in the form of ciprofloxacin hydrochloride monohydrate...

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Hauptverfasser: FEIKUS SZILVIA, FEKETE PAL, ZSIGMOND ZSOLT, FELLNER GYORGYNE, PALFI ZOLTANNE, JAMBOR ISTVANNE, GORA LASZLONE
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creator FEIKUS SZILVIA
FEKETE PAL
ZSIGMOND ZSOLT
FELLNER GYORGYNE
PALFI ZOLTANNE
JAMBOR ISTVANNE
GORA LASZLONE
description Immediate release pharmaceutical composition contains ciprofloxacin, a binder, disintegrant agent and optionally further pharmaceutical auxiliary agents, namely related to the total weight of the composition 60 - 80 % by weight of ciprofloxacin (in the form of ciprofloxacin hydrochloride monohydrate), 2 - 10 % by weight of maltodextrin, 5 - 15 % by weight of disintegrant agent of carboxy methyl starch type, 3 - 6 % by weight of silicium dioxide, 1 - 3 % by weight of a lubricant and in case of film-coated tablets 2 - 6 % of a film coating layer. Farmaceutická kompozícia s bezprostredným uvoľnením obsahuje ciprofloxacín, spojivo, prostriedok podporujúci rozpadavosť a prípadne ďalšie farmaceutické pomocné prostriedky, a to vzhľadom na celkovú hmotnosť kompozície 60 - 80 % hmotnostných ciprofloxacínu (vo forme monohydrátu ciprofloxacín- hydrochloridu), 2 - 10 % hmotnostných maltodextrínu, 5 - 15 % hmotnostných prostriedku podporujúceho rozpadavosť karboxymetylškrobového typu, 3 - 6 % hmotnostných oxidu kremičitého, 1 - 3 % hmotnostné klzného prostriedku a v prípade tabliet s filmovým poťahom 2 - 6 % filmovej poťahovej vrstvy.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Pharmaceutical composition containing ciprofloxacin and method for the preparation thereof
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