Derivatives of hydroxyphenylsulfanylbenzoic and hydroxyphenylsulfanylarylacetic acids

Described are derivatives of hydroxyphenylsulfanylbenzoic and hydroxyphenylsulfanylarylacetic acids of formula (I), wherein X is H, halogen or NO2 group, n is 0 or 1, and m is 2 to 4 if Z is either 4-acetyl-3-hydroxy-2-propylphenoxy of formula (II) or a piperazinyl residue, or m is 1 if Z is quinoli...

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Hauptverfasser: JANDERA ANTONIN, KUCHAR MIROSLAV, JIRICKOVA HANA, KMONICEK VOJTECH, BUCHAROVA VERA, BRUNOVA BOHUMILA, PANAJOTOVA VLADIMIRA
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creator JANDERA ANTONIN
KUCHAR MIROSLAV
JIRICKOVA HANA
KMONICEK VOJTECH
BUCHAROVA VERA
BRUNOVA BOHUMILA
PANAJOTOVA VLADIMIRA
description Described are derivatives of hydroxyphenylsulfanylbenzoic and hydroxyphenylsulfanylarylacetic acids of formula (I), wherein X is H, halogen or NO2 group, n is 0 or 1, and m is 2 to 4 if Z is either 4-acetyl-3-hydroxy-2-propylphenoxy of formula (II) or a piperazinyl residue, or m is 1 if Z is quinolin-2-yl or 6-chloroquinoli-2-yl. Further is described a process for the preparation of these compounds and pharmaceutical compositions containing them as active ingredients. Opísané sú deriváty hydroxyfenylsulfanylbenzoovej kyseliny a hydroxyfenylsulfanylaryloctovej kyseliny vzorca (I), kde X je H, halogén alebo NO2 skupina, a je 0 alebo 1 a m je 2 až 4, ak Z je 4-acetyl-3-hydroxy-2-propylfenoxy vzorca (II) alebo piperazinylový zvyšok. M je 1, ak Z je chinolin-2-yl alebo 6-chlórchinolin-2-yl. Ďalej je opísaný spôsob prípravy týchto zlúčenín a farmaceutické kompozície obsahujúce tieto zlúčeniny ako účinné zložky.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Derivatives of hydroxyphenylsulfanylbenzoic and hydroxyphenylsulfanylarylacetic acids
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