Oral dosage form for improved upper gastrointestinal tract safety
An oral dosage form to be delivered to the stomach comprising a safe and effective amount of an active ingredient selected from the group consisting of tetracycline antibiotics, iron preparations, quinidine, nonsteroidal anti-inflammatory drugs, alprenolol, ascorbic acid, captopril, theophylline, zi...
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| creator | DANSEREAU RICHARD JOHN BEKKER PETRUS JAKOBUS |
| description | An oral dosage form to be delivered to the stomach comprising a safe and effective amount of an active ingredient selected from the group consisting of tetracycline antibiotics, iron preparations, quinidine, nonsteroidal anti-inflammatory drugs, alprenolol, ascorbic acid, captopril, theophylline, zidovoudine, bisphosphonates or mixtures thereof and pharmaceutically acceptable excipients. It has oval form, including the modified modal form or modified caplet shape, is coated to facilitate rapid esophageal transit and avoid irritation in the mouth, buccal cavity, pharynx, and esophagus and has length of from 0.58 cm to 2.16 cm, width of from 0.28 cm to 1.02 cm and thickness of from 0.19 cm to 0.76 cm.
Ústna dávkovacia forma, ktorá má byť dopravená do žalúdka, pozostáva z bezpečného a účinného množstva aktívnej zložky vybranej zo skupiny zahrnujúcej tetracyklínové antibiotiká, prípravky železa, chinidín, nesteroidné protizápalové lieky, alprenolol, kyselinu askorbovú, kaptopril, teofylín, zidovudin, bisfosfonát alebo ich zmesi a farmaceuticky prijateľných masťových základov. Má oválny tvar, vrátane upraveného oválneho tvaru alebo upraveného tvaru kapsuly, je potiahnutá na umožnenie rýchleho prechodu pažerákom a zabránenie podráždeniu v ústach, tvárovej dutine, hltana a pažeráka a má dĺžku od 0,58 cm do 2,16 cm, šírku od 0,28 cm do 1,02 cm a hrúbku od 0,19 cm do 0,76 cm. |
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Ústna dávkovacia forma, ktorá má byť dopravená do žalúdka, pozostáva z bezpečného a účinného množstva aktívnej zložky vybranej zo skupiny zahrnujúcej tetracyklínové antibiotiká, prípravky železa, chinidín, nesteroidné protizápalové lieky, alprenolol, kyselinu askorbovú, kaptopril, teofylín, zidovudin, bisfosfonát alebo ich zmesi a farmaceuticky prijateľných masťových základov. Má oválny tvar, vrátane upraveného oválneho tvaru alebo upraveného tvaru kapsuly, je potiahnutá na umožnenie rýchleho prechodu pažerákom a zabránenie podráždeniu v ústach, tvárovej dutine, hltana a pažeráka a má dĺžku od 0,58 cm do 2,16 cm, šírku od 0,28 cm do 1,02 cm a hrúbku od 0,19 cm do 0,76 cm.</description><edition>7</edition><language>eng ; slo</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2005</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050908&DB=EPODOC&CC=SK&NR=284690B6$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25544,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050908&DB=EPODOC&CC=SK&NR=284690B6$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DANSEREAU RICHARD JOHN</creatorcontrib><creatorcontrib>BEKKER PETRUS JAKOBUS</creatorcontrib><title>Oral dosage form for improved upper gastrointestinal tract safety</title><description>An oral dosage form to be delivered to the stomach comprising a safe and effective amount of an active ingredient selected from the group consisting of tetracycline antibiotics, iron preparations, quinidine, nonsteroidal anti-inflammatory drugs, alprenolol, ascorbic acid, captopril, theophylline, zidovoudine, bisphosphonates or mixtures thereof and pharmaceutically acceptable excipients. It has oval form, including the modified modal form or modified caplet shape, is coated to facilitate rapid esophageal transit and avoid irritation in the mouth, buccal cavity, pharynx, and esophagus and has length of from 0.58 cm to 2.16 cm, width of from 0.28 cm to 1.02 cm and thickness of from 0.19 cm to 0.76 cm.
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Ústna dávkovacia forma, ktorá má byť dopravená do žalúdka, pozostáva z bezpečného a účinného množstva aktívnej zložky vybranej zo skupiny zahrnujúcej tetracyklínové antibiotiká, prípravky železa, chinidín, nesteroidné protizápalové lieky, alprenolol, kyselinu askorbovú, kaptopril, teofylín, zidovudin, bisfosfonát alebo ich zmesi a farmaceuticky prijateľných masťových základov. Má oválny tvar, vrátane upraveného oválneho tvaru alebo upraveného tvaru kapsuly, je potiahnutá na umožnenie rýchleho prechodu pažerákom a zabránenie podráždeniu v ústach, tvárovej dutine, hltana a pažeráka a má dĺžku od 0,58 cm do 2,16 cm, šírku od 0,28 cm do 1,02 cm a hrúbku od 0,19 cm do 0,76 cm.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Oral dosage form for improved upper gastrointestinal tract safety |
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