Cephalosporin antibiotics

The present invention includes novel (7R)-7-(acylamino)-3- (arylthio)-3-cephem-4-carboxylic acids or their pharmacologically acceptable salts which exhibit antibiotic activity against a wide spectrum of organisms including organisms which are resistant to 'beta'-lactam antibiotics and are...

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Hauptverfasser: HECKER SCOTT, GLINKA TOMASZ, LEE VING J, CHO IN-SEOP, ZHANG ZHIJIA J
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creator HECKER SCOTT
GLINKA TOMASZ
LEE VING J
CHO IN-SEOP
ZHANG ZHIJIA J
description The present invention includes novel (7R)-7-(acylamino)-3- (arylthio)-3-cephem-4-carboxylic acids or their pharmacologically acceptable salts which exhibit antibiotic activity against a wide spectrum of organisms including organisms which are resistant to 'beta'-lactam antibiotics and are useful as antibacterial agents. The invention also relates to novel intermediates useful for making the novel compounds of the present invention and to novel methods for producing the novel compounds and intermediate compounds. Zlúčeniny všeobecného vzorca (III) a (II) a ich farmakologicky prijateľné soli, ktoré vykazujú antibiotickú aktivitu voči širokému spektru mikroorganizmov, medzi ktoré patria organizmy rezistentné voči beta-laktámovým antibiotikám, a antibakteriálne činidlá s ich obsahom. Ďalej sú opísané medziprodukty na prípravu uvedených zlúčenín.ŕ
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Cephalosporin antibiotics
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