COMBINED PHARMACEUTICAL PREPARATION FOR TREATMENT OF HUMAN TUMOUR CELLS, USE OF O6-BENZYLGUANINE AND TEMOZOLOMIDE FOR ITS PRODUCTION AND PHARMACEUTICAL KITE

Kombinovaný farmaceutický prostriedok na simultánne, oddelené alebo postupné použitie na liečbu ľudských nádorových buniek obsahuje účinné množstvo O6-benzylguanínu a účinné množstvo temozolomidu s jedným alebo viacerými farmaceuticky prijateľnými nosičmi. Je opísané aj použitie O6-benzylguanínu a t...

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Hauptverfasser: BAER JOHN COLIN, WATSON AMANDA JEAN, MARGISON GEOFFREY PAUL, NEWLANDS EDWARD STUART, RAFFERTY JOSEPH ANTHONY, FREEMAN AZADEH ALISON
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creator BAER JOHN COLIN
WATSON AMANDA JEAN
MARGISON GEOFFREY PAUL
NEWLANDS EDWARD STUART
RAFFERTY JOSEPH ANTHONY
FREEMAN AZADEH ALISON
description Kombinovaný farmaceutický prostriedok na simultánne, oddelené alebo postupné použitie na liečbu ľudských nádorových buniek obsahuje účinné množstvo O6-benzylguanínu a účinné množstvo temozolomidu s jedným alebo viacerými farmaceuticky prijateľnými nosičmi. Je opísané aj použitie O6-benzylguanínu a temozolomidu na prípravu farmaceutického prostriedku na liečbu ľudských nádorových buniek a farmaceutický kit, ktorý obsahuje oddelene farmaceutický prostriedok temezolomid a oddelene farmaceutický prostriedok O6-benzylguanín.ŕ The toxicity of temozolomide, an anti-tumour agent useful in the treatment of various mammalian neoplasms, can be potentiated by the prior administration of an ATase inhibiting agent, i.e., O -benzylguanine.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title COMBINED PHARMACEUTICAL PREPARATION FOR TREATMENT OF HUMAN TUMOUR CELLS, USE OF O6-BENZYLGUANINE AND TEMOZOLOMIDE FOR ITS PRODUCTION AND PHARMACEUTICAL KITE
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