CYCLOSPORINS, METHOD OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEM CONTAINING

CYCLOSPORINS, METHOD OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEM CONTAINING

Cyclosporins wherein the residue at the 1-position has the formula (I) in which -x-y- is -CH=CH-(trans) or -CH2-CH2-; X is oxygen or sulphur and R is hydrogen, optionally halo or hydroxy substituted-C1-3-alkyl, -alkoxy or -alkylthio, or amino or mono- or di-(C1-2alkyl)- amino, useful as pharmaceutic...

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Bibliographische Detailangaben
Hauptverfasser: NAEF RET, PAYNE TREVOR G, EBERLE MARCEL K, BOELSTERLI JOHANN J
Format: Patent
Sprache:eng ; slo
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Cyclosporins wherein the residue at the 1-position has the formula (I) in which -x-y- is -CH=CH-(trans) or -CH2-CH2-; X is oxygen or sulphur and R is hydrogen, optionally halo or hydroxy substituted-C1-3-alkyl, -alkoxy or -alkylthio, or amino or mono- or di-(C1-2alkyl)- amino, useful as pharmaceuticals, preferentially for topical administration in particular for asthma therapy.