MONOHYDRATE AND CRYSTALLINE FORMS OF 6-((3S,4S)-4-METHYL-1- (PYRIMIDIN-2-YLMETHYL)PYRROLIDIN-3-YL)-3-TETRAHYDROPYRAN-4-YL- 7H-IMID AZO (1,5- A) PYRAZIN-8-ONE

MONOHYDRATE AND CRYSTALLINE FORMS OF 6-((3S,4S)-4-METHYL-1- (PYRIMIDIN-2-YLMETHYL)PYRROLIDIN-3-YL)-3-TETRAHYDROPYRAN-4-YL- 7H-IMID AZO (1,5- A) PYRAZIN-8-ONE

The present disclosure relates to crystalline polymorph forms of 6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-tetrahydropyran-4-yl-7H-imidazo[1,5-a]pyrazin-8-one.

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Hauptverfasser: STRATFORD Samuel Alexander, BUTTAR Suzanne, PITAK Mateusz, PATTERSON Adam Ross, DAI Kuangchu, SOVAGO Ioana, XU Jun, ZHOU Peng, WEI Haojuan
Format: Patent
Sprache:eng ; slv
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator STRATFORD Samuel Alexander
BUTTAR Suzanne
PITAK Mateusz
PATTERSON Adam Ross
DAI Kuangchu
SOVAGO Ioana
XU Jun
ZHOU Peng
WEI Haojuan
description The present disclosure relates to crystalline polymorph forms of 6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-tetrahydropyran-4-yl-7H-imidazo[1,5-a]pyrazin-8-one.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title MONOHYDRATE AND CRYSTALLINE FORMS OF 6-((3S,4S)-4-METHYL-1- (PYRIMIDIN-2-YLMETHYL)PYRROLIDIN-3-YL)-3-TETRAHYDROPYRAN-4-YL- 7H-IMID AZO (1,5- A) PYRAZIN-8-ONE
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