PROCESS FOR PREPARING N-(5-((4-(4-((DIMETHYLAMINO)METHYL)-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YL)AMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDE BY REACTING THE CORRESPONDING AMINE WITH A 3-HALO-PROPIONYL CHLORIDE

The present invention provides an improved process for preparing an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors. Additionally...

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Bibliographische Detailangaben
Hauptverfasser: SHIN Woo-Seob, PARK Su-Min, HWANG Yoon-Ah, LIM Jong-Chul, PARK Dae-Gyu, KHOO Ja-Heouk, LEE Seong-Ran, JU Hyun, OH Sang-Ho
Format: Patent
Sprache:eng ; slv
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