BISPECIFIC T CELL ACTIVATING ANTIGEN BINDING MOLECULES

The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells. In addition, the present invention relates to polynucleotides encoding such bispecific antigen binding molecules, and vectors and host cells comprisi...

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Hauptverfasser: KLOSTERMANN Stefan, REGULA Joerg Thomas, SCHAEFER Wolfgang, BACAC Marina, MOLHOJ Michael, NEUMANN (formally JAEGER) Christiane, KLEIN Christian, AST Oliver, IMHOF-JUNG Sabine, UMANA Pablo
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creator KLOSTERMANN Stefan
REGULA Joerg Thomas
SCHAEFER Wolfgang
BACAC Marina
MOLHOJ Michael
NEUMANN (formally JAEGER) Christiane
KLEIN Christian
AST Oliver
IMHOF-JUNG Sabine
UMANA Pablo
description The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells. In addition, the present invention relates to polynucleotides encoding such bispecific antigen binding molecules, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the bispecific antigen binding molecules of the invention, and to methods of using these bispecific antigen binding molecules in the treatment of disease.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title BISPECIFIC T CELL ACTIVATING ANTIGEN BINDING MOLECULES
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