METHOD FOR THE SYNTHESIS OF PENTOSTATIN
The present invention relates to a method for the stereo-selective production of pentostatin comprising an enzymatic transglycosylation reaction between an imidazo-[4,5- d ]-[1,3]diazepine compound and a 2'-deoxyribonucleotide, followed by an ruthenium-catalyzed asymmetric transfer hydrogenatio...
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| creator | SYPCHENKO Volodymyr SCHICKANEDER Christian MATVIIENKO Iaroslav ZABUDKIN Oleksandr |
| description | The present invention relates to a method for the stereo-selective production of pentostatin comprising an enzymatic transglycosylation reaction between an imidazo-[4,5- d ]-[1,3]diazepine compound and a 2'-deoxyribonucleotide, followed by an ruthenium-catalyzed asymmetric transfer hydrogenation. |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY DERIVATIVES THEREOF ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HETEROCYCLIC COMPOUNDS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY SPIRITS SUGARS VINEGAR WINE |
| title | METHOD FOR THE SYNTHESIS OF PENTOSTATIN |
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