THIENO(2,3-C)PYRANS AS CFTR MODULATORS

The present invention discloses compounds according to Formula I: Wherein R 1 is as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment cy...

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Bibliographische Detailangaben
Hauptverfasser: KELGTERMANS Hans, DROPSIT-MONTOVERT Sebastien Jean-Jacques Cedric, MARTINA Sebastien Laurent Xavier, ANDREWS Martin James Inglis, VAN DER PLAS Steven Emiel
Format: Patent
Sprache:eng ; slv
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Zusammenfassung:The present invention discloses compounds according to Formula I: Wherein R 1 is as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment cystic fibrosis by administering a compound of the invention.