Pharmaceutical composition with slow release of trimetazidine

Pharmaceutical composition with slow release of trimetazidine

Composition for prolonged release of trimetazidine, comprises an inner phase comprising trimetazidine and an outer layer comprising a retardant and an antiagglomerant. An independent claim is included for preparing the composition comprising coating the neutral cores with trimetazidine and the binde...

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Hauptverfasser: Hermelin Christophe, Genty Patrick, Pean Jean-Manuel
Format: Patent
Sprache:eng ; slv
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator Hermelin Christophe
Genty Patrick
Pean Jean-Manuel
description Composition for prolonged release of trimetazidine, comprises an inner phase comprising trimetazidine and an outer layer comprising a retardant and an antiagglomerant. An independent claim is included for preparing the composition comprising coating the neutral cores with trimetazidine and the binder to form minigranules, coating the minigranules with the retardant, the plasticizer and the antiagglomerant, and filling the coated minigranules into capsules, optionally in the presence of a lubricant. ACTIVITY : Antianginal; Ophthalmological; Auditory. MECHANISM OF ACTION : None given.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Pharmaceutical composition with slow release of trimetazidine
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