SALTS AND POLYMORPHS OF 8-FLUORO-2-(4-((METHYLAMINO)METHYL)PHENYL)-1,3,4,5-TETRAHYDRO-6H-AZEPINO(5,4,3-CD)INDOL-6-ONE
The present invention relates to novel polymorphic forms of 8-fluoro-2-{4-[(methylamino)methyl]phenyf}-1,3,4,5-tetrahydro-6H-azepino(5,4,3-cd]indol-6-one;(I), and to processes for their preparation. Such polymorphic forms may be a component of a pharmaceutical composition and may be used to treat a...
Gespeichert in:
| Hauptverfasser: | , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; slv |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | CAMPETA Anthony Michael JONES Matthew Cameron GILLMORE Adam KOUGOULOS Eleftherios BASFORD Patricia Ann WALTON Robert LUTHRA Suman |
| description | The present invention relates to novel polymorphic forms of 8-fluoro-2-{4-[(methylamino)methyl]phenyf}-1,3,4,5-tetrahydro-6H-azepino(5,4,3-cd]indol-6-one;(I), and to processes for their preparation. Such polymorphic forms may be a component of a pharmaceutical composition and may be used to treat a mammalian disease condition mediated by poly(ADP-ribose) polymerase activity including the disease condition such as cancer. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_SI2534153TT2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>SI2534153TT2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_SI2534153TT23</originalsourceid><addsrcrecordid>eNqNi7EKwjAURbs4iPoPcUuhb2jTFNfQpKSQ5pUmDnUpReIkWqj-vwH9AKdz4J67Td5OGO-IsJL0aMYOh147gg05QWPOOCAUQEugtFNej0Z0rcX062mvlY2APGNZmXHwyg9CjzKeKg3iovoYUx43BrVMWyvRQAVo1T7Z3Ob7Gg4_7pJjo3ytISzPKazLfA2P8JpcW3BW5px5X7B_mg8XFjfk</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>SALTS AND POLYMORPHS OF 8-FLUORO-2-(4-((METHYLAMINO)METHYL)PHENYL)-1,3,4,5-TETRAHYDRO-6H-AZEPINO(5,4,3-CD)INDOL-6-ONE</title><source>esp@cenet</source><creator>CAMPETA Anthony Michael ; JONES Matthew Cameron ; GILLMORE Adam ; KOUGOULOS Eleftherios ; BASFORD Patricia Ann ; WALTON Robert ; LUTHRA Suman</creator><creatorcontrib>CAMPETA Anthony Michael ; JONES Matthew Cameron ; GILLMORE Adam ; KOUGOULOS Eleftherios ; BASFORD Patricia Ann ; WALTON Robert ; LUTHRA Suman</creatorcontrib><description>The present invention relates to novel polymorphic forms of 8-fluoro-2-{4-[(methylamino)methyl]phenyf}-1,3,4,5-tetrahydro-6H-azepino(5,4,3-cd]indol-6-one;(I), and to processes for their preparation. Such polymorphic forms may be a component of a pharmaceutical composition and may be used to treat a mammalian disease condition mediated by poly(ADP-ribose) polymerase activity including the disease condition such as cancer.</description><language>eng ; slv</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240731&DB=EPODOC&CC=SI&NR=2534153T2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240731&DB=EPODOC&CC=SI&NR=2534153T2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CAMPETA Anthony Michael</creatorcontrib><creatorcontrib>JONES Matthew Cameron</creatorcontrib><creatorcontrib>GILLMORE Adam</creatorcontrib><creatorcontrib>KOUGOULOS Eleftherios</creatorcontrib><creatorcontrib>BASFORD Patricia Ann</creatorcontrib><creatorcontrib>WALTON Robert</creatorcontrib><creatorcontrib>LUTHRA Suman</creatorcontrib><title>SALTS AND POLYMORPHS OF 8-FLUORO-2-(4-((METHYLAMINO)METHYL)PHENYL)-1,3,4,5-TETRAHYDRO-6H-AZEPINO(5,4,3-CD)INDOL-6-ONE</title><description>The present invention relates to novel polymorphic forms of 8-fluoro-2-{4-[(methylamino)methyl]phenyf}-1,3,4,5-tetrahydro-6H-azepino(5,4,3-cd]indol-6-one;(I), and to processes for their preparation. Such polymorphic forms may be a component of a pharmaceutical composition and may be used to treat a mammalian disease condition mediated by poly(ADP-ribose) polymerase activity including the disease condition such as cancer.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNi7EKwjAURbs4iPoPcUuhb2jTFNfQpKSQ5pUmDnUpReIkWqj-vwH9AKdz4J67Td5OGO-IsJL0aMYOh147gg05QWPOOCAUQEugtFNej0Z0rcX062mvlY2APGNZmXHwyg9CjzKeKg3iovoYUx43BrVMWyvRQAVo1T7Z3Ob7Gg4_7pJjo3ytISzPKazLfA2P8JpcW3BW5px5X7B_mg8XFjfk</recordid><startdate>20240731</startdate><enddate>20240731</enddate><creator>CAMPETA Anthony Michael</creator><creator>JONES Matthew Cameron</creator><creator>GILLMORE Adam</creator><creator>KOUGOULOS Eleftherios</creator><creator>BASFORD Patricia Ann</creator><creator>WALTON Robert</creator><creator>LUTHRA Suman</creator><scope>EVB</scope></search><sort><creationdate>20240731</creationdate><title>SALTS AND POLYMORPHS OF 8-FLUORO-2-(4-((METHYLAMINO)METHYL)PHENYL)-1,3,4,5-TETRAHYDRO-6H-AZEPINO(5,4,3-CD)INDOL-6-ONE</title><author>CAMPETA Anthony Michael ; JONES Matthew Cameron ; GILLMORE Adam ; KOUGOULOS Eleftherios ; BASFORD Patricia Ann ; WALTON Robert ; LUTHRA Suman</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_SI2534153TT23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; slv</language><creationdate>2024</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>CAMPETA Anthony Michael</creatorcontrib><creatorcontrib>JONES Matthew Cameron</creatorcontrib><creatorcontrib>GILLMORE Adam</creatorcontrib><creatorcontrib>KOUGOULOS Eleftherios</creatorcontrib><creatorcontrib>BASFORD Patricia Ann</creatorcontrib><creatorcontrib>WALTON Robert</creatorcontrib><creatorcontrib>LUTHRA Suman</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CAMPETA Anthony Michael</au><au>JONES Matthew Cameron</au><au>GILLMORE Adam</au><au>KOUGOULOS Eleftherios</au><au>BASFORD Patricia Ann</au><au>WALTON Robert</au><au>LUTHRA Suman</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SALTS AND POLYMORPHS OF 8-FLUORO-2-(4-((METHYLAMINO)METHYL)PHENYL)-1,3,4,5-TETRAHYDRO-6H-AZEPINO(5,4,3-CD)INDOL-6-ONE</title><date>2024-07-31</date><risdate>2024</risdate><abstract>The present invention relates to novel polymorphic forms of 8-fluoro-2-{4-[(methylamino)methyl]phenyf}-1,3,4,5-tetrahydro-6H-azepino(5,4,3-cd]indol-6-one;(I), and to processes for their preparation. Such polymorphic forms may be a component of a pharmaceutical composition and may be used to treat a mammalian disease condition mediated by poly(ADP-ribose) polymerase activity including the disease condition such as cancer.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; slv |
| recordid | cdi_epo_espacenet_SI2534153TT2 |
| source | esp@cenet |
| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | SALTS AND POLYMORPHS OF 8-FLUORO-2-(4-((METHYLAMINO)METHYL)PHENYL)-1,3,4,5-TETRAHYDRO-6H-AZEPINO(5,4,3-CD)INDOL-6-ONE |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T13%3A31%3A13IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=CAMPETA%20Anthony%20Michael&rft.date=2024-07-31&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ESI2534153TT2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |