A process and intermediate compounds for the preparation of amlodipine benzene sulphonate

A process and intermediate compounds for the preparation of amlodipine benzene sulphonate

A subject matter of the invention is a process for preparing 3-ÄethylÜ-5-ÄmethylÜ-2-Ä2'-(aminoethoxy)-methylÜ-4--Ä2''-(chloro)-phen ylÜ-6-ÄmethylÜ-1,4-di-ÄhydroÜ-pyridine-3,5-di-ÄcarboxylateÜ benzenesulfonic acid salt of Formula in which 3-ÄethylÜ-5-ÄmethylÜ-2-Ä2'-(yl)-ethoxy-met...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: BLASKO GABOR DR, KOVANYI GYOERGYI LAX DR, NAGY KALMAN DR, KRASZNAI GYOERGY, TOEMPE PETER DR, NEMETH NORBERT, BOZSING DANIEL DR, SIMIG GYULA DR, VERECZKEY GYOERGYI DONATH, NEMET GABOR
Format: Patent
Sprache:eng ; slv
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator BLASKO GABOR DR
KOVANYI GYOERGYI LAX DR
NAGY KALMAN DR
KRASZNAI GYOERGY
TOEMPE PETER DR
NEMETH NORBERT
BOZSING DANIEL DR
SIMIG GYULA DR
VERECZKEY GYOERGYI DONATH
NEMET GABOR
description A subject matter of the invention is a process for preparing 3-ÄethylÜ-5-ÄmethylÜ-2-Ä2'-(aminoethoxy)-methylÜ-4--Ä2''-(chloro)-phen ylÜ-6-ÄmethylÜ-1,4-di-ÄhydroÜ-pyridine-3,5-di-ÄcarboxylateÜ benzenesulfonic acid salt of Formula in which 3-ÄethylÜ-5-ÄmethylÜ-2-Ä2'-(yl)-ethoxy-methylÜ-4-Ä2''-(chloro)-phenylÜ -6-ÄmethylÜ-1,4-di-ÄhydroÜ-pyridine-3,5-di-ÄcarboxylateÜ hexaminium iodide of Formula is reacted with benzenesulfonic acid of Formula Several variants comprise also reactions for preparing intermediates leading to the said end product. A further subject matter of the invention are intermediates for preparing the said end product.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_SI0902016TT1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>SI0902016TT1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_SI0902016TT13</originalsourceid><addsrcrecordid>eNqNy7EKwjAQgOEuDqK-w_kAQqsgOIooOpvFqZzNhQaauyOXLj69GXwAp3_5_mXzOoNmGcgMkD1ELpQT-YiFYJCkMrM3CJKhjFQpKWYsURgkAKZJfNTIBG_iD9XaPOkoXPd1swg4GW1-XTXb29Vd7jtS6ckUh-pL_3y0p3bfdkfnusM_5gsgCjue</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>A process and intermediate compounds for the preparation of amlodipine benzene sulphonate</title><source>esp@cenet</source><creator>BLASKO GABOR DR ; KOVANYI GYOERGYI LAX DR ; NAGY KALMAN DR ; KRASZNAI GYOERGY ; TOEMPE PETER DR ; NEMETH NORBERT ; BOZSING DANIEL DR ; SIMIG GYULA DR ; VERECZKEY GYOERGYI DONATH ; NEMET GABOR</creator><creatorcontrib>BLASKO GABOR DR ; KOVANYI GYOERGYI LAX DR ; NAGY KALMAN DR ; KRASZNAI GYOERGY ; TOEMPE PETER DR ; NEMETH NORBERT ; BOZSING DANIEL DR ; SIMIG GYULA DR ; VERECZKEY GYOERGYI DONATH ; NEMET GABOR</creatorcontrib><description>A subject matter of the invention is a process for preparing 3-ÄethylÜ-5-ÄmethylÜ-2-Ä2'-(aminoethoxy)-methylÜ-4--Ä2''-(chloro)-phen ylÜ-6-ÄmethylÜ-1,4-di-ÄhydroÜ-pyridine-3,5-di-ÄcarboxylateÜ benzenesulfonic acid salt of Formula in which 3-ÄethylÜ-5-ÄmethylÜ-2-Ä2'-(yl)-ethoxy-methylÜ-4-Ä2''-(chloro)-phenylÜ -6-ÄmethylÜ-1,4-di-ÄhydroÜ-pyridine-3,5-di-ÄcarboxylateÜ hexaminium iodide of Formula is reacted with benzenesulfonic acid of Formula Several variants comprise also reactions for preparing intermediates leading to the said end product. A further subject matter of the invention are intermediates for preparing the said end product.</description><edition>7</edition><language>eng ; slv</language><creationdate>2002</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20020831&amp;DB=EPODOC&amp;CC=SI&amp;NR=0902016T1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20020831&amp;DB=EPODOC&amp;CC=SI&amp;NR=0902016T1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BLASKO GABOR DR</creatorcontrib><creatorcontrib>KOVANYI GYOERGYI LAX DR</creatorcontrib><creatorcontrib>NAGY KALMAN DR</creatorcontrib><creatorcontrib>KRASZNAI GYOERGY</creatorcontrib><creatorcontrib>TOEMPE PETER DR</creatorcontrib><creatorcontrib>NEMETH NORBERT</creatorcontrib><creatorcontrib>BOZSING DANIEL DR</creatorcontrib><creatorcontrib>SIMIG GYULA DR</creatorcontrib><creatorcontrib>VERECZKEY GYOERGYI DONATH</creatorcontrib><creatorcontrib>NEMET GABOR</creatorcontrib><title>A process and intermediate compounds for the preparation of amlodipine benzene sulphonate</title><description>A subject matter of the invention is a process for preparing 3-ÄethylÜ-5-ÄmethylÜ-2-Ä2'-(aminoethoxy)-methylÜ-4--Ä2''-(chloro)-phen ylÜ-6-ÄmethylÜ-1,4-di-ÄhydroÜ-pyridine-3,5-di-ÄcarboxylateÜ benzenesulfonic acid salt of Formula in which 3-ÄethylÜ-5-ÄmethylÜ-2-Ä2'-(yl)-ethoxy-methylÜ-4-Ä2''-(chloro)-phenylÜ -6-ÄmethylÜ-1,4-di-ÄhydroÜ-pyridine-3,5-di-ÄcarboxylateÜ hexaminium iodide of Formula is reacted with benzenesulfonic acid of Formula Several variants comprise also reactions for preparing intermediates leading to the said end product. A further subject matter of the invention are intermediates for preparing the said end product.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2002</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNy7EKwjAQgOEuDqK-w_kAQqsgOIooOpvFqZzNhQaauyOXLj69GXwAp3_5_mXzOoNmGcgMkD1ELpQT-YiFYJCkMrM3CJKhjFQpKWYsURgkAKZJfNTIBG_iD9XaPOkoXPd1swg4GW1-XTXb29Vd7jtS6ckUh-pL_3y0p3bfdkfnusM_5gsgCjue</recordid><startdate>20020831</startdate><enddate>20020831</enddate><creator>BLASKO GABOR DR</creator><creator>KOVANYI GYOERGYI LAX DR</creator><creator>NAGY KALMAN DR</creator><creator>KRASZNAI GYOERGY</creator><creator>TOEMPE PETER DR</creator><creator>NEMETH NORBERT</creator><creator>BOZSING DANIEL DR</creator><creator>SIMIG GYULA DR</creator><creator>VERECZKEY GYOERGYI DONATH</creator><creator>NEMET GABOR</creator><scope>EVB</scope></search><sort><creationdate>20020831</creationdate><title>A process and intermediate compounds for the preparation of amlodipine benzene sulphonate</title><author>BLASKO GABOR DR ; KOVANYI GYOERGYI LAX DR ; NAGY KALMAN DR ; KRASZNAI GYOERGY ; TOEMPE PETER DR ; NEMETH NORBERT ; BOZSING DANIEL DR ; SIMIG GYULA DR ; VERECZKEY GYOERGYI DONATH ; NEMET GABOR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_SI0902016TT13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; slv</language><creationdate>2002</creationdate><toplevel>online_resources</toplevel><creatorcontrib>BLASKO GABOR DR</creatorcontrib><creatorcontrib>KOVANYI GYOERGYI LAX DR</creatorcontrib><creatorcontrib>NAGY KALMAN DR</creatorcontrib><creatorcontrib>KRASZNAI GYOERGY</creatorcontrib><creatorcontrib>TOEMPE PETER DR</creatorcontrib><creatorcontrib>NEMETH NORBERT</creatorcontrib><creatorcontrib>BOZSING DANIEL DR</creatorcontrib><creatorcontrib>SIMIG GYULA DR</creatorcontrib><creatorcontrib>VERECZKEY GYOERGYI DONATH</creatorcontrib><creatorcontrib>NEMET GABOR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BLASKO GABOR DR</au><au>KOVANYI GYOERGYI LAX DR</au><au>NAGY KALMAN DR</au><au>KRASZNAI GYOERGY</au><au>TOEMPE PETER DR</au><au>NEMETH NORBERT</au><au>BOZSING DANIEL DR</au><au>SIMIG GYULA DR</au><au>VERECZKEY GYOERGYI DONATH</au><au>NEMET GABOR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>A process and intermediate compounds for the preparation of amlodipine benzene sulphonate</title><date>2002-08-31</date><risdate>2002</risdate><abstract>A subject matter of the invention is a process for preparing 3-ÄethylÜ-5-ÄmethylÜ-2-Ä2'-(aminoethoxy)-methylÜ-4--Ä2''-(chloro)-phen ylÜ-6-ÄmethylÜ-1,4-di-ÄhydroÜ-pyridine-3,5-di-ÄcarboxylateÜ benzenesulfonic acid salt of Formula in which 3-ÄethylÜ-5-ÄmethylÜ-2-Ä2'-(yl)-ethoxy-methylÜ-4-Ä2''-(chloro)-phenylÜ -6-ÄmethylÜ-1,4-di-ÄhydroÜ-pyridine-3,5-di-ÄcarboxylateÜ hexaminium iodide of Formula is reacted with benzenesulfonic acid of Formula Several variants comprise also reactions for preparing intermediates leading to the said end product. A further subject matter of the invention are intermediates for preparing the said end product.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; slv
recordid cdi_epo_espacenet_SI0902016TT1
source esp@cenet
title A process and intermediate compounds for the preparation of amlodipine benzene sulphonate
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T19%3A37%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=BLASKO%20GABOR%20DR&rft.date=2002-08-31&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ESI0902016TT1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true