Analytical elements containing non-reactive blocking dyes

Analytical elements containing non-reactive blocking dyes

It is known to assay an analyte by measuring the reflectance density in the range 320 to 360nm using a reflectometer. The analyte is placed on an analytical element which comprises a reagent layer and a registration layer. However, in some cases the reflectometer used to carry out the assay has a ma...

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Hauptverfasser: APPELL CHARLES HOWARD, JACOBS MERRITT NYLES, DETWILER RICHARD LINN, HAMANN JOHN ERIC, NEALON DANIEL ANTHONY
Format: Patent
Sprache:eng
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INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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creator APPELL CHARLES HOWARD
JACOBS MERRITT NYLES
DETWILER RICHARD LINN
HAMANN JOHN ERIC
NEALON DANIEL ANTHONY
description It is known to assay an analyte by measuring the reflectance density in the range 320 to 360nm using a reflectometer. The analyte is placed on an analytical element which comprises a reagent layer and a registration layer. However, in some cases the reflectometer used to carry out the assay has a maximum obtainable reflectance density of 1.5 and for some assays the maximum reflectance density generated may be 2.0 at 340nm. Described herein is a blocking dye which has a low absorbtivity band from 320 to 360nm and a high absorbtivity band from 640 to 720nm which can be incorporated into either the reagent layer or the registration layer of the element to improve the precision and dynamic range of the assay.
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subjects INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
title Analytical elements containing non-reactive blocking dyes
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