Ethylamido fluorenes and improved method of making same
Novel substituted fluorene compunds of Formula I are active as melatonergic agents: wherein: X= H, halogen, OH or OZ; Z= C1-6 alkyl; -(CH2)m-CF3 (m=0-2); CD3; or n=1 or 2; and R= C1-6 alkyl, C3-6 cycloalkyl, C2-4 alkenyl, halogen substituted C1-6 alkyl, or C1-6 alkoxy substituted C1-6 alkyl.
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| creator | LEBULLUEC, KAREN, L YEVICH, JOSEPH, P TAKAKI, KATHERINE, S EPPERSON, JAMES, R KARAGEORGE, GEORGE, N WATSON, BRETT, T |
| description | Novel substituted fluorene compunds of Formula I are active as melatonergic agents: wherein: X= H, halogen, OH or OZ; Z= C1-6 alkyl; -(CH2)m-CF3 (m=0-2); CD3; or n=1 or 2; and R= C1-6 alkyl, C3-6 cycloalkyl, C2-4 alkenyl, halogen substituted C1-6 alkyl, or C1-6 alkoxy substituted C1-6 alkyl. |
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Z= C1-6 alkyl; -(CH2)m-CF3 (m=0-2); CD3; or n=1 or 2; and R= C1-6 alkyl, C3-6 cycloalkyl, C2-4 alkenyl, halogen substituted C1-6 alkyl, or C1-6 alkoxy substituted C1-6 alkyl.</description><edition>6</edition><language>eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; APPARATUS THEREFOR ; CHEMISTRY ; GENERAL METHODS OF ORGANIC CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1998</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19980417&DB=EPODOC&CC=SG&NR=48454A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76419</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19980417&DB=EPODOC&CC=SG&NR=48454A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LEBULLUEC, KAREN, L</creatorcontrib><creatorcontrib>YEVICH, JOSEPH, P</creatorcontrib><creatorcontrib>TAKAKI, KATHERINE, S</creatorcontrib><creatorcontrib>EPPERSON, JAMES, R</creatorcontrib><creatorcontrib>KARAGEORGE, GEORGE, N</creatorcontrib><creatorcontrib>WATSON, BRETT, T</creatorcontrib><title>Ethylamido fluorenes and improved method of making same</title><description>Novel substituted fluorene compunds of Formula I are active as melatonergic agents: wherein: X= H, halogen, OH or OZ; 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Z= C1-6 alkyl; -(CH2)m-CF3 (m=0-2); CD3; or n=1 or 2; and R= C1-6 alkyl, C3-6 cycloalkyl, C2-4 alkenyl, halogen substituted C1-6 alkyl, or C1-6 alkoxy substituted C1-6 alkyl.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Ethylamido fluorenes and improved method of making same |
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